| Autor: |
Uchida IA; Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada., Lee CP, Byrnes EM |
| Jazyk: |
angličtina |
| Zdroj: |
American journal of human genetics [Am J Hum Genet] 1975 May; Vol. 27 (3), pp. 419-29. |
| Abstrakt: |
Epidemiological studies suggest radiation exposure as a cause of meiotic non-disjunction in humans, but experimental evidence with cytological proof has been lacking. Our results indicate that mitotic nondisjunction of lymphocyte chromosomes can also be induced by exposure to a low dose of radiation. Abnormal segregation can be induced not only when the cells are irradiated but also when nonirradiated cells are incubated with irradiated cell-free plasma or serum. The X and no. 21 chromosomes appear particularly susceptible to nondisjunction. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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