| Autor: |
Klioze SS, Allen RC, Wilker JC, Woodward DL |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of medicinal chemistry [J Med Chem] 1980 Jun; Vol. 23 (6), pp. 677-9. |
| DOI: |
10.1021/jm00180a020 |
| Abstrakt: |
The synthesis and antihypertensive activity of several piperidinebenzenesulfenamides related to the previously reported potent hypotensive agents 1 and a series of 1-arypiperazine-4-benzenesulfenamides 7 are described. A number of the latter compounds exhibit marked antihypertensive properties. The most interesting of these compounds, 7a and 7k, have been evaluated in several other animal models. In addition, benzenesulfinamides 9a and 9b and benzensulfonamides 10a and 10b have been prepared for comparison purposes. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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