| Autor: |
Asnis GM, Sachar EJ, Halbreich U, Ostrow LC, Nathan RS, Halpern FS |
| Jazyk: |
angličtina |
| Zdroj: |
Psychiatry research [Psychiatry Res] 1981 Aug; Vol. 5 (1), pp. 39-45. |
| DOI: |
10.1016/0165-1781(81)90059-7 |
| Abstrakt: |
The prolactin (PRL) response to 0.5 mg i.m. of reserpine was compared to 0.5 mg i.m. of haloperidol in eight young men. The fact that reserpine was found to be a potent releaser of PRL--significantly greater than haloperidol--suggests a major role of storage pool dopamine in regulating PRL Secretion. Since the PRL response to neuroleptics is highly correlated with clinical potency, reserpine could be a potent antipsychotic, and further clinical trials are indicated. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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