[Participation of the H-2 system in regulating the sensitivity of mice to morphine].

Autor: Maĭskiĭ AI, Vedernikova NN, Volov VA
Jazyk: ruština
Zdroj: Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1978 Jun; Vol. 85 (6), pp. 688-90.
Abstrakt: The pain susceptibility of congenic-resistant mouse strains A/Sn, C3H/Sn and C57BL/10 Sn after the injection of morphine was studied. Strains sensitive and resistant to this narcotic were distinguished among congenic-resistant A/Sn and C3H/Sn mice. The morphine sensitivity inheritance is characterized by dominance. The possibility of the major histocompatibility mouse system (H-2) participation in the genetic control of mouse susceptibility to morphine is discussed.
Databáze: MEDLINE