| Autor: |
Axen K, Haas SS, Haas F, Gaudino D, Haas A |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of applied physiology: respiratory, environmental and exercise physiology [J Appl Physiol Respir Environ Exerc Physiol] 1983 Oct; Vol. 55 (4), pp. 1211-8. |
| DOI: |
10.1152/jappl.1983.55.4.1211 |
| Abstrakt: |
Ventilatory responses to inspiratory elastic and resistive loads of 67 men were analyzed. During the 1st, 5th, and 10th consecutively loaded breaths 1) individual responses ranged from a rapid-shallow to a slow-deep breathing pattern; 2) strong tidal volume (VT) defenders employed longer inspirations than did weak VT defenders; and 3) individual frequency responses were mediated by changes in inspiratory and/or expiratory timing. Thus the group response was qualitatively similar on the 1st, 5th, and 10th loaded breaths. Quantitatively, however, the group's mean minute ventilation increased throughout each episode owing to progressively larger tidal volumes coupled with equal breathing frequencies. During elastic loading this amplified VT defense was achieved by stronger inspirations with no systematic changes in timing, whereas during resistive loading it was achieved both by stronger and longer inspirations. Inspiring 5% CO2 induced a degree of hypercapnia exceeding that accompanying mechanical loading and yet elicited a comparatively modest enhancement of respiratory output. These findings suggest that in conscious humans 1) repeated mechanical loading activates neural load-compensating mechanisms; 2) the range of these neural adjustments varies with both load size and type; and 3) the stimulus to initiate this behavior is largely nonchemical. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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