Stereospecificity of the ferric enterobactin receptor of Escherichia coli K-12.

Autor: Neilands JB, Erickson TJ, Rastetter WH
Jazyk: angličtina
Zdroj: The Journal of biological chemistry [J Biol Chem] 1981 Apr 25; Vol. 256 (8), pp. 3831-2.
Abstrakt: Synthetic enterobactin and enantioenterobactin (D-seryl enterobactin) have been examined for the ability to transport iron in Escherichia coli. Failure of the unnatural, D-serine-derived material to support growth of E. coli mutants indicates outer membrane receptor specificity for the naturally occurring complex having an L-seryl backbone and the delta-cis configuration of the Fe(III).catecholate center. Enantioenterobactin was markedly less effective in protecting cells against colicin B compared to synthetic or natural enterobactin.
Databáze: MEDLINE