[Pre-operative endoscopic infusions of an adsorbent containing mitomycin C (MMC-CH44) in stomach cancer].

Autor: Hagiwara A, Takahashi T, Ueda T, Takeda M, Lee R, Mizuguchi N
Jazyk: japonština
Zdroj: Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 1983 Dec; Vol. 10 (12), pp. 2558-64.
Abstrakt: Small charcoal particles adsorbing Mitomycin C (MMC-CH) were used in the treatment of lymphnode metastasis of gastric cancer. Immediately after injection of MMC-CH into the gastric wall, lymph capillaries and regional lymphnodes were stained in black and the high concentration of MMC was delivered with charcoal particles. MMC-CH was injected preoperatively using endoscope into the gastric wall of 20 patients with gastric cancer. MMC-CH was observed in 70% of metastatic regional lymphnodes. Systemic side effect was not noted at all. Erosion and shallow ulcers were observed at the site of injection but no perforation occurred.
Databáze: MEDLINE