| Autor: |
Whitfill CE, Allen J, Gyles NR, Thoma J, Patterson LT |
| Jazyk: |
angličtina |
| Zdroj: |
Poultry science [Poult Sci] 1982 Aug; Vol. 61 (8), pp. 1573-8. |
| DOI: |
10.3382/ps.0611573 |
| Abstrakt: |
Blood sera components from Arkansas regressor line (R-line) and progressor line (Pr-line) chickens are compared for the first time for Rous sarcoma virus neutralizing activity. Sera was fractionated by Sephadex G-100 filtration into a high molecular weight fraction I (HMW-I) and a low molecular weight fraction II (LMW-II) component (HMW-I greater than 14,000 daltons, LMW-II less than 5,000 daltons). Both fractions from each line of chickens exhibit activity against Rous sarcoma virus (RSV) judged by a wing web assay. Both HMW-I (principally antibodies) and LMW-II neutralized RSV when obtained from hyperimmune R-chickens and Pr-chickens with large progressing tumors. However, HMW-I and LMW-II obtained from R- or Pr-chickens before challenge contain so RSV neutralizing activity. The novel low molecular weight fraction II disappeared from the sera of R-line chickens 2 weeks after tumor regression, whereas the HMW-I persisted after tumor regression. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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