Effect of antineoplastic drugs on fibroblast proliferation in rabbit aqueous humor.

Autor: Kwong EM, Litin BS, Jones MA, Herschler J
Jazyk: angličtina
Zdroj: Ophthalmic surgery [Ophthalmic Surg] 1984 Oct; Vol. 15 (10), pp. 847-51.
Abstrakt: An assay is described to test the ability of antineoplastic agents to slow fibroblast growth. The effect of bleomycin sulfate, cytosine arabinoside (cytarabine), and 5-fluorouracil on suppression of fibroblast proliferation in 20% rabbit aqueous humor was studied in vitro. All of the drugs exhibited some suppression of fibroblast proliferation at differing doses. The choice of target cell, however, was an important factor in the dose responses obtained.
Databáze: MEDLINE