Autor: |
Goldhirsch A, Pirovino M, Sonntag RW, Tschopp L, Ryssel HJ, Brunner KW |
Jazyk: |
angličtina |
Zdroj: |
Cancer treatment reports [Cancer Treat Rep] 1980 Feb-Mar; Vol. 64 (2-3), pp. 335-7. |
Abstrakt: |
Thirty-eight pretreated patients with Hodgkin's disease (HD) and malignant non-Hodgkin's lymphoma were given combination chemotherapy with VM-26, Adriamycin, bleomycin, and prednisone. Four of 15 evaluable patients with HD achieved a partial remission (PR), with a median duration of 8 months. Of 12 patients with diffuse poorly differentiated lymphocytic lymphoma, one achieved a complete remission (30+ months) and five achieved a PR (median, 6 months). One of three patients with histiocytic lymphoma had a PR of 1.5 months. There was one drug-related death. Five patients developed life-threatening hematologic toxicity. Two HD responders died of acute nonlymphocytic leukemia. |
Databáze: |
MEDLINE |
Externí odkaz: |
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