Autor: |
DeSante KA, Stoll RG, Kaiser DG, DiSanto AR |
Jazyk: |
angličtina |
Zdroj: |
Journal of pharmaceutical sciences [J Pharm Sci] 1977 Dec; Vol. 66 (12), pp. 1713-6. |
DOI: |
10.1002/jps.2600661214 |
Abstrakt: |
Plasma level data on two investigational capsule formulations of propoxyphene with similar physicochemical parameters demonstrate that the formulations have different in vivo bioavailabilities. The potential bioavailability problems with water-soluble drugs and the lack of correlation of in vitro and in vivo parameters for equivalent drug formulations are discussed. |
Databáze: |
MEDLINE |
Externí odkaz: |
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