Factor VIII inhibition associated with chlorpromazine-induced hepatic injury.
| Autor: | Glazier RL, Crowell EB Jr |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Thrombosis and haemostasis [Thromb Haemost] 1977 Jun 30; Vol. 37 (3), pp. 523-6. |
| Abstrakt: | A 90-year-old man was given chlorpromazine for sedation and 2 weeks later developed cholestatic jaundice and subsequently a factor VIII inhibitor. His death 4 weeks after institution of chlorpromazine, from massive bleeding, coupled with the autopsy finding of intrahepatic cholestatic jaundice, suggests that both adverse reactions were due to the drug. |
| Databáze: | MEDLINE |
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