Prophylactic chelation therapy in occupational lead poisoning: a review.

Autor: Bridbord K, Blejer HP
Jazyk: angličtina
Zdroj: American Industrial Hygiene Association journal [Am Ind Hyg Assoc J] 1977 Oct; Vol. 38 (10), pp. 536-42.
DOI: 10.1080/0002889778507667
Abstrakt: Chelating agents are useful in the therapy of acute overexposure to lead. However, prophylactic use of chelating agents, particularly under conditions of continued exposure to lead can be harmful to health. Potential adverse effects include kidney damage, symptomatic lead poisoning, increased absorption of lead from the gastrointestinal tract and disruption in the metabolism of trace metals other than lead. Prophylactic chelation is an unacceptable medical practice which cannot be condoned.
Databáze: MEDLINE