Evolution of bunyaviruses by genome reassortment in dually infected mosquitoes (Aedes triseriatus).

Autor: Beaty BJ, Sundin DR, Chandler LJ, Bishop DH
Jazyk: angličtina
Zdroj: Science (New York, N.Y.) [Science] 1985 Nov 01; Vol. 230 (4725), pp. 548-50.
DOI: 10.1126/science.4048949
Abstrakt: Aedes triseriatus mosquitoes became dually infected after ingesting two mutants of LaCrosse (LAC) virus simultaneously or after ingesting, by interrupted feeding, the two viruses sequentially within a 2-day period. After 2 weeks of incubation, approximately 25 percent of the vectors contained new virus genotypes as the result of RNA segment reassortment. New viruses were transmitted when the mosquitoes fed on mice. Viruses ingested more than 2 days after the initial infecting virus did not cause superinfection of the mosquito vectors.
Databáze: MEDLINE