[Circadian fluctuations in dioxidine toxicity].
Autor: | Gus'kova TA, Liberman SS |
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Jazyk: | ruština |
Zdroj: | Farmakologiia i toksikologiia [Farmakol Toksikol] 1985 Jan-Feb; Vol. 48 (1), pp. 80-2. |
Abstrakt: | It has been established in rat experiments that toxicity of the antibacterial drug dioxydin (1,4-di-N-oxide 2,3-dioxymethylquinoxaline) depends on the time of administration. The drug exhibits the minimal and maximal toxicity upon administration at 8 o'clock p.m. and at 12 o'clock, respectively. |
Databáze: | MEDLINE |
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