Peripheral Arterial Disease Management: Insights From the SerbVasc Registry.

Autor:	Tanaskovic S; Vascular Surgery Clinic, Institute for Cardiovascular Diseases Dedinje, Belgrade, Serbia.; Faculty of Medicine, University of Belgrade, Belgrade, Serbia., Ilijevski N; Vascular Surgery Clinic, Institute for Cardiovascular Diseases Dedinje, Belgrade, Serbia.; Faculty of Medicine, University of Belgrade, Belgrade, Serbia., Davidovic L; Faculty of Medicine, University of Belgrade, Belgrade, Serbia.; Clinic for Vascular and Endovascular Surgery, University Clinical Centre of Serbia, Belgrade, Serbia., Petrovic J; Department for Cardiology and Internal Medicine, Vascular Surgery Clinic, Institute for Cardiovascular Diseases Dedinje, Belgrade, Serbia., Zekic P; Vascular Surgery Clinic, Institute for Cardiovascular Diseases Dedinje, Belgrade, Serbia., Milacic A; Vascular Surgery Clinic, Institute for Cardiovascular Diseases Dedinje, Belgrade, Serbia., Vujcic A; Clinic for Vascular and Endovascular Surgery, University Clinical Centre of Serbia, Belgrade, Serbia., Roganovic A; Clinic for Vascular and Endovascular Surgery, University Clinical Centre of Serbia, Belgrade, Serbia., Martinovic D; Clinical Hospital Centre Zemun, Belgrade, Serbia., Popovic M; Clinical Hospital Centre Zvezdara, Belgrade, Serbia., Crnokrak B; Clinical Hospital Centre Bezanijska Kosa, Belgrade, Serbia., Jokovic V; Centre for Vascular Surgery, University Clinical Centre Kragujevac, Kragujevac, Serbia., Damnjanovic Z; Vascular Surgery Clinic, University Clinical Centre Nis, Nis, Serbia.; Faculty of Medicine, University of Nis, Nis, Serbia., Vukasinovic I; General Hospital Uzice, Uzice, Serbia., Tomic A; Military Medical Academy, Belgrade, Serbia., Zoranovic R; Military Medical Academy, Belgrade, Serbia., Koncar I; Faculty of Medicine, University of Belgrade, Belgrade, Serbia.; Clinic for Vascular and Endovascular Surgery, University Clinical Centre of Serbia, Belgrade, Serbia.
Jazyk:	angličtina
Zdroj:	Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists [J Endovasc Ther] 2024 Dec 04, pp. 15266028241292470. Date of Electronic Publication: 2024 Dec 04.
DOI:	10.1177/15266028241292470
Abstrakt:	Background: This report contributes to VASCUNET data on treating peripheral artery disease (PAD) in Serbia, addressing sex differences, revascularization types, procedure characteristics, and morbidity and mortality. Methods: SerbVasc, part of the VASCUNET collaboration, includes vascular procedures from 27 Serbian hospitals. Data from 1681 PAD patients were analyzed, focusing on sex disparities, diabetes prevalence, previous procedures, infection and tissue loss, and morbidity and mortality rates. Results: Males formed the majority, comprising 1169 (69.5%) of the patients. Men were significantly more often treated open surgically compared to women (77.6% vs 68.0%; p=0.000). Diabetes stood at 40.2% prevalence. Smoking history was noted in 61.9% of patients, predominantly males. Complication rates stood at 7.5%, with diabetic patients more prone to reinterventions and graft restenosis. The in-hospital mortality rate was 1.6%, with significant predictors of mortality including urgent procedures and recent myocardial infarction. The severity of the infection was correlated with diabetes (r=0.250, p=0.000) and previous amputations (r=0.186, p=0.000). Patients undergoing revascularization followed by minor amputations had a significantly lower incidence of major amputation (0.1% vs 2.9%, p=0.000). Conclusions: SerbVasc data provides a comprehensive overview of PAD management, highlighting the significant impact of diabetes and smoking on disease progression and outcomes. Clinical Impact: This study highlights critical aspects of PAD management in developing countries, emphasizing sex differences, risk factors, and outcomes. Males predominated and are more likely to undergo open surgery. Diabetes and smoking significantly influenc disease progression, with diabetic patients experiencing higher rates of graft restenosis and reinterventions. Urgent procedures and recent myocardial infarctions are key predictors of in-hospital mortality. Combining revascularization with minor amputations reduced major amputation rates. These findings provide valuable data for tailoring treatment strategies, optimizing resource allocation, and improving outcomes for PAD patients, with implications extending beyond Serbia to similar healthcare systems. Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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