Beneficial Impact of Vaccination Against SARS-CoV-2 on the Mental Health of IPF Patients.

Autor: Tomos I; 5th Pulmonary Medicine Department, SOTIRIA Thoracic Diseases Hospital of Athens, 11527 Athens, Greece.; 2nd Pulmonary Medicine Department, General University Hospital 'Attikon', Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece., Papaioannou AI; First Academic Department of Pneumonology, SOTIRIA Thoracic Diseases Hospital of Athens, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece., Daniil ZI; Department of Respiratory Medicine, Medical School, University of Thessaly, 41110 Larissa, Greece., Dimeas IE; Department of Respiratory Medicine, Medical School, University of Thessaly, 41110 Larissa, Greece., Kirgou P; Department of Respiratory Medicine, Medical School, University of Thessaly, 41110 Larissa, Greece., Gogali A; Department of Pneumonology, Medical School, University of Ioannina, 45500 Ioannina, Greece., Tatsis K; Department of Pneumonology, Medical School, University of Ioannina, 45500 Ioannina, Greece., Papanikolaou I; Pulmonary Department, Corfu General Hospital, 49100 Corfu, Greece., Tzilas V; 2nd Pulmonary Medicine Department, General University Hospital 'Attikon', Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece., Tzouvelekis A; Department of Respiratory Medicine, General Hospital of Patras, University of Patras, 26500 Patras, Greece., Tsiri P; Department of Respiratory Medicine, General Hospital of Patras, University of Patras, 26500 Patras, Greece., Steiropoulos P; Department of Pneumonology, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, 68100 Alexandroupolis, Greece., Ntolios P; Department of Pneumonology, Medical School, Democritus University of Thrace, University General Hospital of Alexandroupolis, 68100 Alexandroupolis, Greece., Xyfteri A; Private Practice, 24200 Messini, Greece., Antoniou K; Department of Thoracic Medicine and Laboratory of Molecular and Cellular Pneumonology, Medical School, University of Crete, 71500 Heraklion, Greece., Symvoulakis E; Clinic of Social and Family Medicine, Department of Social Medicine, School of Medicine, University of Crete, 71500 Heraklion, Greece., Haritou A; Private Practice, 45500 Ioannina, Greece., Maniati M; Private Practice, 45500 Ioannina, Greece., Kolilekas L; 7th Pulmonary Department, SOTIRIA Thoracic Diseases Hospital of Athens, 15772 Athens, Greece., Antonogiannaki EM; 2nd Pulmonary Medicine Department, General University Hospital 'Attikon', Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece., Apollonatou V; 2nd Pulmonary Medicine Department, General University Hospital 'Attikon', Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece., Kallieri M; 2nd Pulmonary Medicine Department, General University Hospital 'Attikon', Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece., Samaras K; Private Practice, 11527 Athens, Greece., Loukides S; 2nd Pulmonary Medicine Department, General University Hospital 'Attikon', Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece., Karakatsani A; 2nd Pulmonary Medicine Department, General University Hospital 'Attikon', Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece., Bouros D; Iatriko Medical Center and National and Kapodstrian University of Athens, 15125 Athens, Greece., Manali E; 2nd Pulmonary Medicine Department, General University Hospital 'Attikon', Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece., Papiris S; 2nd Pulmonary Medicine Department, General University Hospital 'Attikon', Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Jazyk: angličtina
Zdroj: Advances in respiratory medicine [Adv Respir Med] 2024 Nov 06; Vol. 92 (6), pp. 466-471. Date of Electronic Publication: 2024 Nov 06.
DOI: 10.3390/arm92060042
Abstrakt: Background : Depression and anxiety represent significant comorbidities in idiopathic pulmonary fibrosis (IPF) patients, affecting their quality of life. The COVID-19 pandemic has had an uneven impact on global mental health. The Hospital Anxiety and Depression Scale (HADS) constitutes a validated tool to identify anxiety disorders and depression. The aim of this multicentre study was to evaluate the effect of COVID-19 vaccination on depression and anxiety in IPF patients. Methods : Consecutive IPF patients (median 73.5 years) who are regularly followed-up with were included in the study. Demographics, functional, and clinical were recorded. The HADS score was calculated before and one month after vaccination against COVID-19 in all participants. A Wilcoxon signed ranks test was conducted. Results : A total of 180 IPF patients (median 73.5 years) were included in the study. Among them, 145 patients (81%) received antifibrotic treatment. A significant reduction in HADS, both in anxiety and depression scales, was observed one month after vaccination against SARS-COV-2), independent of age, smoking, lung function impairment, and prior history of depression ( p < 0.01). Conclusions : A higher Hospital Anxiety and Depression Scale score was detected before vaccination against COVID-19. It seems that vaccination also offered a beneficial effect on depression and anxiety in IPF patients, independent of age, smoking, lung function impairment, and prior history of depression.
Databáze: MEDLINE