In-vivo cerebral artery pulsation assessment with Dynamic computed tomography angiography.

Autor: Stam LB; Department of Neurosurgery, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: lotte.stam@radboudumc.nl., Linden SML; Department of Neurosurgery, Radboud University Medical Center, Nijmegen, the Netherlands., Aquarius R; Department of Neurosurgery, Radboud University Medical Center, Nijmegen, the Netherlands., Hering A; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, the Netherlands., Oostveen LJ; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, the Netherlands., Meijer FJA; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, the Netherlands., Boogaarts HD; Department of Neurosurgery, Radboud University Medical Center, Nijmegen, the Netherlands.
Jazyk: angličtina
Zdroj: European journal of radiology [Eur J Radiol] 2024 Nov 13; Vol. 182, pp. 111828. Date of Electronic Publication: 2024 Nov 13.
DOI: 10.1016/j.ejrad.2024.111828
Abstrakt: Four-Dimensional Computed Tomography Angiography (4D CTA) seems a promising technique for capturing vessel motion of cerebral arteries, which may help to assess pathological conditions such as intracranial aneurysms. The goal of our current observational study is to capture the lumen diameter of cerebral arteries during three subsequent cardiac cycles with 4D CTA and to assess vessel motion, anticipating consistent expansion patterns within each cardiac cycle. Eighteen adult patients with unruptured and untreated intracranial aneurysms were recruited at Radboud University Medical Center. Three cardiac cycles were captured, on a wide detector CT system, using ECG-gated 4D CTA. To reduce the impact of small head movements during the acquisition, a rigid-body registration was employed. Three 10 mm segments of cerebral arteries were selected. The total deformation of the vessel lumen was calculated using a deformable registration algorithm and was used as a substitute measure for vessel motion. No pulsations could be registered, which was probably caused by pulsation motion below threshold of detection in combination with insufficient Signal-to-Noise Ratio. Further studies need to investigate if large intracranial structures can be evaluated and if using a novel scanner with a high spatial resolution would result in reproducible measurements of arteries this size.
Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: [Frederick J.A. Meijer reports a relationship with Canon Medical Systems Corporation that includes: speaking and lecture fees. Hieronymus D. Boogaarts reports a relationship with Stryker that includes: consulting or advisory. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.].
(Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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