Impact of remote social interaction during the COVID-19 pandemic on the cognitive and psychological status of older adults with and without cognitive impairment: A randomized controlled study.

Autor: Vives-Rodriguez AL; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America.; Department of Neurology, Boston University School of Medicine, Boston, MA, United States of America., Marin A; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America.; Department of Neurology, Boston University School of Medicine, Boston, MA, United States of America., Schiloski KA; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America., Hajos GP; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America., Di Crosta A; Department of Psychology, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy., Ceccato I; Department of Psychology, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy., La Malva P; Department of Psychology, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy., Anderson DC; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America.; Department of Neurology, Boston University School of Medicine, Boston, MA, United States of America., Lahdo N; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America., Donnelly K; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America., Dong J; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America., Kasha S; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America., Rooney C; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America., Dayaw J; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America., Marton G; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America., Wack A; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America., Hanger V; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America., DeCaro R; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America.; Department of Neurology, Boston University School of Medicine, Boston, MA, United States of America., Di Domenico A; Department of Psychology, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy., Turk KW; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America.; Department of Neurology, Boston University School of Medicine, Boston, MA, United States of America.; Alzheimer's Disease Research Center, Department of Neurology, Boston University School of Medicine, Boston, MA, United States of America., Palumbo R; Department of Psychology, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy., Budson AE; Center for Translational Cognitive Neuroscience, VA Boston Healthcare System, Boston, MA, United States of America.; Department of Neurology, Boston University School of Medicine, Boston, MA, United States of America.; Alzheimer's Disease Research Center, Department of Neurology, Boston University School of Medicine, Boston, MA, United States of America.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2024 Nov 12; Vol. 19 (11), pp. e0311792. Date of Electronic Publication: 2024 Nov 12 (Print Publication: 2024).
DOI: 10.1371/journal.pone.0311792
Abstrakt: Background: Social isolation and loneliness have both been associated with psychological health and cognitive decline in older adults. This study investigated the impact of social interaction through remote communication technologies during the COVID-19 pandemic on the cognitive and psychological status of older adults with and without cognitive impairment.
Methods: Participants were recruited from Boston (USA) and Chieti (Italy). The study used a randomized single-blinded controlled crossover design with an intervention (remote social conversations with research staff over 20-minute video or telephone calls three times per week) and a passive control condition, each one of 4-weeks duration. The primary outcome was a composite cognitive score change from baseline to week 4. Secondary outcomes included scales for mood, anxiety, and loneliness.
Results: Out of 196 participants recruited from April 2020 to April 2021, 17% dropped out. Based on the blind MoCA, 52% had cognitive impairment, and 25% were at risk of social isolation according to the Lubben social network scale. We observed that larger social networks were linked to better cognitive status and lower depression and anxiety levels, while loneliness was directly associated to depression severity. Older adults with cognitive impairment exhibited higher levels of depression and anxiety and were at greater risk for social isolation. In terms of the intervention, 91% preferred telephone over video calls. The intervention did not lead to improvements in cognitive or psychological scores.
Conclusions: More work is needed to assess the utility of this intervention for the support of a heterogenous cross-cultural sample of older adults at-risk for social isolation, including individuals with cognitive impairment. Future research should explore longer intervention periods, categorize participants by call type, and target those meeting social isolation criteria.
Trial Registration: ClinicalTrials.gov NCT04480112.
Competing Interests: The authors have read the journal’s policy and have the following competing interests: Andrew Budson has been a consultant for Eli Lilly and Genentech, and the PI on investigator-initiated trials for Vox Neuro and Bristol Myers Squibb. He also receives book royalties from Elsevier and Oxford University Press. Katherine Turk is a PI on an investigator-initiated study for Vox Neuro. This does not alter our adherence to PLOS ONE policies on sharing data and materials.
(Copyright: This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.)
Databáze: MEDLINE
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