CTK-like syndrome: Corneal opacity and flattening following sequential intracorneal ring implantation and corneal cross-linking.

Autor:	Fontes BM; Department of Ophthalmology and Visual Sciences, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil.; Centro de Microcirurgia & Diagnóstico, Rio de Janeiro, Brazil., Nosé RM; Department of Ophthalmology and Visual Sciences, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil.; Eye Clinic, São Paulo, Brazil., Hafezi F; ELZA Institute, Zurich, Switzerland.; Ocular Cell Biology Group, Center for Applied Biotechnology and Molecular Medicine, University of Zurich, Switzerland.; Faculty of Medicine, University of Geneva, Geneva, Switzerland.; School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.; Department of Ophthalmology at NYU Grossman School of Medicine, New York, NY, USA., Torres-Netto EA; Department of Ophthalmology and Visual Sciences, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil.; ELZA Institute, Zurich, Switzerland.; Ocular Cell Biology Group, Center for Applied Biotechnology and Molecular Medicine, University of Zurich, Switzerland.; Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Jazyk:	angličtina
Zdroj:	American journal of ophthalmology case reports [Am J Ophthalmol Case Rep] 2024 Oct 25; Vol. 36, pp. 102196. Date of Electronic Publication: 2024 Oct 25 (Print Publication: 2024).
DOI:	10.1016/j.ajoc.2024.102196
Abstrakt:	Purpose: This is a case report of a 31-year-old male patient presenting progressive and markedly asymmetric keratoconus treated with sequential intracorneal ring segment (ICRS) implantation followed by accelerated corneal cross-linking (CXL). Observations: The follow-up after the last procedure revealed a thin, opacified cornea with an unexpected massive flattening of up to 20.3 D. The central flattening attributed to the individual effect of CXL (post-ICRS-implant vs. post-CXL) was 19.1 D. Conclusions and Importance: This original case reports how CXL followed by ICRS implant may result in an early and extreme corneal remodeling. Moreover, such an unusual combination of extreme corneal flattening, thinning, and opacification may imitate a clinical manifestation of central toxic keratopathy and suggests that eyes with ICRS implantation must be followed closely if CXL is performed sequentially after. Competing Interests: The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: The authors have no conflict of interest. (© 2024 The Authors.)
Databáze:	MEDLINE
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