Montmorillonite: An advanced material with diverse pharmaceutical and medicinal applications.

Autor:	Fatale S; Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Education and Research, Near Karwand Naka, Shirpur, India., Patil JK; Department of Pharmacognasy. PSGVPM'S College of Pharmacy, Shahada, India., Pardeshi CV; Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Education and Research, Near Karwand Naka, Shirpur, India., Pande VV; Department of Pharmaceutics, RSMs N.N. Sattha College of Pharmacy, Ahamadnagar, India., Bhutkar MA; Department of Pharmaceutics, Rajaram Bapu College of Pharmacy, Kasegaon, India., Parashar K; Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Education and Research, Near Karwand Naka, Shirpur, India., Sonawane RO; Department of Pharmaceutics, R.C. Patel Institute of Pharmaceutical Education and Research, Near Karwand Naka, Shirpur, India. Electronic address: raju_sonawane1979@rediffmail.com.
Jazyk:	angličtina
Zdroj:	Annales pharmaceutiques francaises [Ann Pharm Fr] 2024 Nov 06. Date of Electronic Publication: 2024 Nov 06.
DOI:	10.1016/j.pharma.2024.11.001
Abstrakt:	Montmorillonite (MMT) clay is composed of naturally layered silicate. The clays were more popular in the pharmaceutical and other various fields due to their beneficial physicochemical properties viz. non-toxicity, high surface area, efficient adsorption capability, high swellability, high dispersibility, thixotropic behaviour, and cation exchange capacity. Chemically modified clay provides significant opportunities in variety of applications. MMT finds very crucial place in pharmaceutical field owing to its medicinal properties, which may be used to delay the drug release in chronic physiological conditions and the targeted drug release as well. It is also used to improve the dissolution rate of certain drug molecules, which increased the attention of the researchers to explore the MMT for drug delivery applications. MMT clay has been used as pharmaceutical aids viz. suspending agent, lubricant, anticaking agent, diluent, emulsifier, nanocomposites-forming material, and sometimes filler. MMT clay have been investigated in the fabrication of different pharmaceutical formulations viz. hydrogel, films, nanocomposites, and matrix-based systems. MMT has obtained industrial importance due to its adsorption property and also finds use in wastewater treatment. Other than this, MMT also finds applications in cosmetic industry, food industry, and paper industry. Considering the wide applicability of MMT, it is need of an hour to explore the MMT for further commercial exploitation. Competing Interests: Disclosure of interest The authors declare that they have no competing interest. (Copyright © 2024. Published by Elsevier Masson SAS.)
Databáze:	MEDLINE
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