Carcinoid heart findings in vasoactive intestinal peptide-secreting tumour.

Autor: Joshi M; Internal Medicine, Harbor-UCLA Medical Center Department of Internal Medicine, Torrance, California, USA mjoshi2@dhs.lacounty.gov., Aldea D; Division of Cardiology, Department of Medicine, Harbor-UCLA Medical Center, Torrance, California, USA., Ngo P; Hematology and Oncology, Harbor-UCLA Medical Center Department of Internal Medicine, Torrance, California, USA., Shah S; Division of Cardiology, Department of Medicine, Harbor-UCLA Medical Center, Torrance, California, USA.
Jazyk: angličtina
Zdroj: BMJ case reports [BMJ Case Rep] 2024 Nov 07; Vol. 17 (11). Date of Electronic Publication: 2024 Nov 07.
DOI: 10.1136/bcr-2024-262229
Abstrakt: Tricuspid valve disease in carcinoid heart syndrome is usually diagnosed via screening echocardiography in patients with known carcinoid syndrome. Vasoactive intestinal peptide tumour (VIPoma) is a rare tumour with an incidence of 0.05%-2% that typically presents with symptoms related to the release of vasoactive intestinal peptide: flushing, diarrhoea and electrolyte abnormalities like hypokalaemia and hypochlorhydria. Historically, the cardiac valves are unaffected. We present a case where a finding of tricuspid regurgitation and stenosis on echocardiography prompted an expedited workup for malignancy ultimately leading to a diagnosis of VIPoma.
Competing Interests: Competing interests: None declared.
(© BMJ Publishing Group Limited 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze: MEDLINE