Health-related quality of life due to malaria: a systematic review.

Autor: Andrade MV; Centre of Regional Planning and Development (Cedeplar-UFMG), Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.; Núcleo de Avaliação de Tecnologias em Saúde (NATS) do Hospital das ClínicasUniversidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Noronha K; Centre of Regional Planning and Development (Cedeplar-UFMG), Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.; Núcleo de Avaliação de Tecnologias em Saúde (NATS) do Hospital das ClínicasUniversidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Guedes GR; Centre of Regional Planning and Development (Cedeplar-UFMG), Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Diniz BC; Centre of Regional Planning and Development (Cedeplar-UFMG), Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Silva VA; Centre of Regional Planning and Development (Cedeplar-UFMG), Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., de Souza A; Centre of Regional Planning and Development (Cedeplar-UFMG), Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., de Carvalho LR; Centre of Regional Planning and Development (Cedeplar-UFMG), Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Braga PE; Centre of Regional Planning and Development (Cedeplar-UFMG), Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Motta-Santos AS; Centre of Regional Planning and Development (Cedeplar-UFMG), Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.; Núcleo de Avaliação de Tecnologias em Saúde (NATS) do Hospital das ClínicasUniversidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Julião NA; Centre of Regional Planning and Development (Cedeplar-UFMG), Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.; Núcleo de Avaliação de Tecnologias em Saúde (NATS) do Hospital das ClínicasUniversidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., da Silva DN; Centre of Regional Planning and Development (Cedeplar-UFMG), Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Bracarense H; Centre of Regional Planning and Development (Cedeplar-UFMG), Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Castro MC; Department of Global Health and Population, Harvard T.H. Chan School of Public Health, 665 Huntington Av. Building I, Room 1102A, Boston, MA, 02115, USA. mcastro@hsph.harvard.edu.
Jazyk: angličtina
Zdroj: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation [Qual Life Res] 2024 Nov 06. Date of Electronic Publication: 2024 Nov 06.
DOI: 10.1007/s11136-024-03822-w
Abstrakt: Purpose: This paper aims to conduct a systematic review (SR) to assess Health-Related Quality of Life (HRQoL) of malaria-exposed populations for different regions where malaria is endemic, considering any health measurements.
Methods: An electronic search of the Medline, Lilacs, and Embase databases was conducted until February 2nd, 2024, to identify and select studies that evaluated HRQoL. No restrictions on place or language were made.
Results: Thirty-seven studies were included, among them 21 focused on African countries. The most investigated HRQoL outcome associated with malaria was Disability-Adjusted Life Years (DALYs). These studies primarily aim to analyze the epidemiological burden of the disease or to conduct economic assessments. Only four studies conducted field research using specific instruments to assess the HRQoL of individuals experiencing malaria episodes. Three of them estimated EQ-5D utility index and found scores varying from 0.349 for severe malaria (Indonesia) to 0.74 (Nigeria). The health domains that are most affected by malaria are pain and discomfort and usual activities (EQ-5D instrument) and physical domains (WHOQOL-BREF). These results reflect the main malaria symptoms which are fever, headache, and generalized pain.
Conclusion: This SR highlights a significant gap in understanding the quality of life among individuals experiencing malaria. Despite being an acute illness, recurrent episodes of malaria can lead to considerable loss in quality of life. Moreover, there are significant equity implications, as malaria remains endemic in socioeconomically disadvantaged populations.
(© 2024. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)
Databáze: MEDLINE
Externí odkaz: