Unlocking Single-Particle Multiparametric Sensing: Decoupling Temperature and Viscosity Readouts through Upconverting Polarized Spectroscopy.

Autor: Ortiz-Rivero E; Nanomaterials for Bioimaging Group, Departamento de Física de Materiales, Facultad de Ciencias, Universidad Autónoma de Madrid, Madrid, 28049, Spain.; Instituto de Materiales Nicolás Cabrera, Universidad Autónoma de Madrid, Madrid, 28049, Spain., Prorok K; Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, Wroclaw, 50-422, Poland., Marin R; Nanomaterials for Bioimaging Group, Departamento de Física de Materiales, Facultad de Ciencias, Universidad Autónoma de Madrid, Madrid, 28049, Spain.; Instituto de Materiales Nicolás Cabrera, Universidad Autónoma de Madrid, Madrid, 28049, Spain.; Institute for Advanced Research in Chemical Sciences (IAdChem), Universidad Autónoma de Madrid, Madrid, 28049, Spain., Bednarkiewicz A; Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, Wroclaw, 50-422, Poland., Jaque D; Nanomaterials for Bioimaging Group, Departamento de Física de Materiales, Facultad de Ciencias, Universidad Autónoma de Madrid, Madrid, 28049, Spain.; Institute for Advanced Research in Chemical Sciences (IAdChem), Universidad Autónoma de Madrid, Madrid, 28049, Spain., Haro-González P; Nanomaterials for Bioimaging Group, Departamento de Física de Materiales, Facultad de Ciencias, Universidad Autónoma de Madrid, Madrid, 28049, Spain.; Instituto de Materiales Nicolás Cabrera, Universidad Autónoma de Madrid, Madrid, 28049, Spain.; Institute for Advanced Research in Chemical Sciences (IAdChem), Universidad Autónoma de Madrid, Madrid, 28049, Spain.
Jazyk: angličtina
Zdroj: Small methods [Small Methods] 2024 Nov 03, pp. e2400718. Date of Electronic Publication: 2024 Nov 03.
DOI: 10.1002/smtd.202400718
Abstrakt: Upconverting particles (UCPs), renowned for their capability to convert infrared to visible light, serve as invaluable imaging probes. Furthermore, their responsiveness to diverse external stimuli holds promise for leveraging UCPs as remote multiparametric sensors, capable of characterizing medium properties in a single assessment. However, the utility of UCPs in multiparametric sensing is impeded by crosstalk, wherein distinct external stimuli induce identical alterations in UCP luminescence, hindering accurate interpretation, and yielding erroneous outputs. Overcoming crosstalk requires alternative strategies in upconverting luminescence analysis. In this study, it is shown how a single spinning NaYF 4 :Er 3+ , Yb 3+ upconverting particle enables simultaneous and independent readings of temperature and viscosity. This is achieved by decoupling thermal and rehological measurements-employing the luminescence of thermally-coupled energy levels of Er 3+ ions for thermal sensing, while leveraging the polarization of luminescence from non-thermally coupled levels of Er 3+ ions to determine viscosity. Through simple proof-of-concept experiments, the study validates the capability of a single spinning UCP to perform unbiased, simultaneous temperature, and viscosity sensing, thereby opening new avenues for advanced sensing in microenvironments.
(© 2024 The Author(s). Small Methods published by Wiley‐VCH GmbH.)
Databáze: MEDLINE
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