Six-year course over time and predictors of suicidal ideation in depressed older patients.

Autor: Zuidersma M; University of Groningen, University Medical Centre Groningen, Department of Psychiatry, Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), 9700 RB Groningen, the Netherlands. Electronic address: m.zuidersma@umcg.nl., de Vries YA; Department of Child and Adolescent Psychiatry, University of Groningen, University Medical Center Groningen (UMCG), Groningen, the Netherlands., Bogers ICHM; University of Groningen, University Medical Centre Groningen, Department of Psychiatry, Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), 9700 RB Groningen, the Netherlands., Rhebergen D; GGZ Centraal Mental Health Care, Amersfoort, the Netherlands; Amsterdam Public Health Research Institute, Mental Health Program, Amsterdam, the Netherlands; Department of Psychiatry, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands., Oude Voshaar RC; University of Groningen, University Medical Centre Groningen, Department of Psychiatry, Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), 9700 RB Groningen, the Netherlands.
Jazyk: angličtina
Zdroj: Journal of affective disorders [J Affect Disord] 2024 Oct 29; Vol. 370, pp. 90-99. Date of Electronic Publication: 2024 Oct 29.
DOI: 10.1016/j.jad.2024.10.097
Abstrakt: Background: It is important to know predictors of long-term course over time of suicidal thoughts and ideation in depressed older persons.
Methods: In this study, 378 depressed older persons were interviewed at baseline, and after 2 and 6 years to evaluate the presence of depressive disorder. The Inventory of Depressive Symptomatology (IDS) was administered every 6 months for 6 years. Latent Class Growth Analysis was performed on the IDS item on suicidal ideation to identify subgroups with different trajectories.
Results: Five subgroups with suicidal ideation trajectories were identified: 1) severe, transient (10.9 %), 2) severe, persisting (8.0 %), 3) mild, but increasing (14.9 %), 4) moderate, persisting (35.6 %), and 5) no thoughts (30.6 %). Mixed model analysis showed that trajectories were related to 6-year course of depressive symptoms. Yet, suicidal ideation or thoughts of loss of meaning of life were still present in 22.7 % and 17.4 % of those who remitted after 2 and 6 years. Independent of baseline depressive symptom severity, loneliness, childhood trauma, history of suicidal ideation or attempt, openness to experience, earlier age of depression onset, anxiety symptom severity and worse mastery predicted worse trajectories.
Limitations: 47 % dropped out at 6-years follow-up, we did not distinguish between thoughts of death and suicide, we did not assess death by suicide.
Conclusions: Although trajectories of suicidal ideation and thoughts of loss of meaning of life were strongly related to the course of depression severity, they also appear after remission. Clinicians should be vigilant for suicidal ideation or death wish, even after remission of depression.
Competing Interests: Declaration of competing interest None.
(Copyright © 2024. Published by Elsevier B.V.)
Databáze: MEDLINE
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