Transforming cancer detection and treatment with nanoflowers.

Autor: Prajapati BG; Shree S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Kherva, Gujarat, 384012, India.; Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand., Verma K; Division of Cardiology, Department of Internal Medicine, LSU Health Sciences Center, 1501 Kings Hwy, Shreveport, LA, 71103, USA., Sharma S; Department of Pharmacy, Banasthali Vidyapith, Banasthali, Rajasthan, 304022, India. skspharmacology@gmail.com., Kapoor DU; Dr. Dayaram Patel Pharmacy College, Bardoli, Gujarat, 394601, India. dev7200@gmail.com.
Jazyk: angličtina
Zdroj: Medical oncology (Northwood, London, England) [Med Oncol] 2024 Oct 22; Vol. 41 (11), pp. 295. Date of Electronic Publication: 2024 Oct 22.
DOI: 10.1007/s12032-024-02530-2
Abstrakt: Nanoflowers, an innovative class of nanoparticles with a distinctive flower-like structure, have garnered significant interest for their straightforward synthesis, remarkable stability, and heightened efficiency. Nanoflowers demonstrate versatile applications, serving as highly sensitive biosensors for rapidly and accurately detecting conditions such as diabetes, Parkinson's, Alzheimer's, and foodborne infections. Nanoflowers, with their intricate structure, show significant potential for targeted drug delivery and site-specific action, while also exhibiting versatility in applications such as enzyme purification, water purification from dyes and heavy metals, and gas sensing through materials like nickel oxide. This review also addresses the structural characteristics, surface modification, and operational mechanisms of nanoflowers. The nanoflowers play a crucial role in preventing premature drug leakage from nanocarriers. Additionally, the nanoflowers contribute to averting systemic toxicity and suboptimal therapy efficiency caused by hypoxia in the tumor microenvironment during chemotherapy and photodynamic therapy. This review entails the role of nanoflowers in cancer diagnosis and treatment. In the imminent future, the nanoflowers system is poised to revolutionize as a smart material, leveraging its exceptional surface-to-volume ratio to significantly augment adsorption efficiency across its intricate petals. This review delves into the merits and drawbacks of nanoflowers, exploring synthesis techniques, types, and their evolving applications in cancer.
(© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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