Age dependence of the average refractive index of the isolated human crystalline lens.

Autor:	Natarajan R; Ophthalmic Biophysics Laboratory, L V Prasad Eye Institute, Hyderabad, Telangana, India., Maceo Heilman B; Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.; Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, USA., Ruggeri M; Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.; Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, USA., Ho A; Ophthalmic Biophysics Laboratory, L V Prasad Eye Institute, Hyderabad, Telangana, India.; Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, USA.; Brien Holden Vision Institute Limited, Sydney, NSW, Australia.; School of Optometry and Vision Science, The University of New South Wales, Sydney, NSW, Australia., Singh VM; Ophthalmic Biophysics Laboratory, L V Prasad Eye Institute, Hyderabad, Telangana, India.; Cataract & Refractive Surgery Services, L V Prasad Eye Institute, Hyderabad, Telangana, India., Augusteyn R; School of Optometry and Vision Science, The University of New South Wales, Sydney, NSW, Australia., Parel JM; Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.; Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, USA., Vaddavalli PK; Ophthalmic Biophysics Laboratory, L V Prasad Eye Institute, Hyderabad, Telangana, India.; Cataract & Refractive Surgery Services, L V Prasad Eye Institute, Hyderabad, Telangana, India.; Shantilal Shanghvi Cornea Institute, L V Prasad Eye Institute, Hyderabad, Telangana, India., Manns F; Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.; Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, USA.
Jazyk:	angličtina
Zdroj:	Biomedical optics express [Biomed Opt Express] 2024 Sep 17; Vol. 15 (10), pp. 5901-5911. Date of Electronic Publication: 2024 Sep 17 (Print Publication: 2024).
DOI:	10.1364/BOE.536501
Abstrakt:	We measured the average group refractive index (RI) of 120 isolated lenses from 120 human donors (age: 0.03 to 61 years). The average group RI was calculated from a measurement of the optical thickness of the lens using optical coherence tomography and the apparent window shift of the test chamber caused by the lens. The estimated measurement uncertainty was ±0.004. The group RI at 880 nm was converted to phase RI at 589 nm using the dispersion equation of water and protein. From 2 to 61 years, the mean value of the RI was 1.415 ± 0.002 (group index at 880 nm) and 1.406 ± 0.002 (phase index at 589 nm) independent of age (p = 0.774). Two lenses from donors of age 0.33 and 3 months had significantly lower RI (group index: 1.405 and 1.403; phase index: 1.396 and 1.394). From age 2 to 61, the average lens RI is constant with age within the measurement uncertainty (±0.004). Competing Interests: There are no financial interests to disclose. (© 2024 Optica Publishing Group.)
Databáze:	MEDLINE
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