The value of coronary calcium score in predicting clinical outcomes in patients with chronic coronary syndrome.

Autor: Elnagar B; Cardiovascular Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt. drbasmaelnagar12@gmail.com., Habib M; Cardiovascular Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt., Elnagar R; Radiology Department, Faculty of Medicine, Tanta University, Tanta, Egypt., Khalfallah M; Cardiovascular Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Jazyk: angličtina
Zdroj: BMC cardiovascular disorders [BMC Cardiovasc Disord] 2024 Oct 17; Vol. 24 (1), pp. 567. Date of Electronic Publication: 2024 Oct 17.
DOI: 10.1186/s12872-024-04157-7
Abstrakt: Background: Coronary artery atherosclerosis and calcification are the precursors to the development of coronary artery disease and its complications. Coronary artery calcium scoring (CACS) is useful as a risk-stratification tool in coronary artery disease.
Objective: The current study was designed to identify the relationship between CACS and major adverse cardiovascular outcomes in patients with stable coronary artery disease.
Methods: The study was conducted on 435 patients with stable ischemic heart disease. The patients were classified into two groups according to their coronary artery calcium score (CACS): group I (n = 220 patients), whose calcium score was mild to moderate (< 400), and group II (n = 215 patients), whose calcium score was high (≥ 400). All patients were closely monitored for two years to assess major adverse cardiovascular events (MACE).
Results: After 2 years of follow-up, MACE drastically increased in Group II in the form of unstable angina, myocardial infarction, demand for percutaneous coronary intervention, and heart failure. Multivariate regression analysis showed that age ≥ 55 years, Framingham risk score > 10, CACS ≥ 400, body mass index ≥ 30 kg/m2, and the proximal lesions of the vessels were the independent risk factors for major cardiac events.
Conclusion: The coronary calcium score is a distinct feature of coronary atherosclerosis, and a score of 400 or higher is a reliable, noninvasive predictor of the progression of coronary artery diseases and their consequences, including MACE.
(© 2024. The Author(s).)
Databáze: MEDLINE
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