Are females getting more fatigable as they age?

Autor: Bertrand MF; Laboratoire Interuniversitaire de Biologie de la Motricité, Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, 42023, Saint-Etienne, France., Varesco G; Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.; Center for Advanced Research in Sleep Medicine (CEAMS), Hôpital du Sacré-Coeur de Montréal, CIUSSS du Nord de l'Île-de- Montréal, Montreal, QC, Canada.; Institut National du Sport du Québec, Montréal, QC, Canada., Millet GY; Laboratoire Interuniversitaire de Biologie de la Motricité, Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, 42023, Saint-Etienne, France.; IUF, Institut Universitaire de France, Paris, France., Féasson L; Laboratoire Interuniversitaire de Biologie de la Motricité, Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, 42023, Saint-Etienne, France.; Unité de Myologie, Service de Physiologie Clinique et de l'Exercice, Centre Référent Maladies Neuromusculaires Euro-NmD, CHU de Saint-Etienne, Saint-Etienne, France., Lapole T; Laboratoire Interuniversitaire de Biologie de la Motricité, Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, 42023, Saint-Etienne, France.; IUF, Institut Universitaire de France, Paris, France., Rozand V; CAPS, Inserm UMR1093, UFR des Sciences du Sport, Faculté des Sciences du Sport, Université de Bourgogne, BP 27877, 21078, Dijon, France. vianney.rozand@u-bourgogne.fr.
Jazyk: angličtina
Zdroj: European journal of applied physiology [Eur J Appl Physiol] 2024 Oct 17. Date of Electronic Publication: 2024 Oct 17.
DOI: 10.1007/s00421-024-05637-6
Abstrakt: Purpose: The aim of this study was to compare performance fatigability between young (n = 13; 18-35 yr.; 23.5 ± 3.3 yr.), old (n = 13; 60-79 yr.; 68.2 ± 4.3 yr.), and very old (n = 11; ≥ 80 yr.; 85.6 ± 1.8 yr.) females during single-limb isometric (ISO) vs. isokinetic concentric (CON) vs. cycling (BIKE) fatiguing tasks.
Methods: Participants randomly performed three incremental fatiguing tasks where increments were set as percentage of body weight to better reflect the daily life: (1) ISO and (2) CON consisted of stages of 75 contractions (120 s, 0.8 s on/0.8 s off) on an isokinetic dynamometer and (3) BIKE consisted of stages of 120 s at 37.5 rpm with similar duty cycle. Knee extensors maximal force, voluntary activation and potentiated twitch amplitude were measured at baseline, after each stage and at exhaustion.
Results: Compared to young, exercise performance was 20% and 53% lower in old and very old females in ISO, 46% and 76% lower in CON and 32% and 62% lower in BIKE (all p < 0.01). For a given workload (i.e. common stages), performance fatigability (i.e. force loss) was greater for very old compared to young females in CON only (p = 0.018). At exhaustion, performance fatigability was similar across groups and conditions (~ 30%; all p > 0.05), with similar impairments in both voluntary activation and twitch amplitude.
Conclusion: These results emphasize the importance of the kind of fatiguing task and modalities of evaluation when investigating the effects of aging on performance fatigability.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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