Optimization of image reconstruction technique for respiratory-gated lung stereotactic body radiotherapy treatment planning using four-dimensional CT: a phantom study.

Autor: Yasue K; Department of Radiological Sciences, Ibaraki Prefectural University of Health Sciences, 4669-2, Ami, Inashiki, Ibaraki, 300-0394, Japan. yasueke@ipu.ac.jp., Fuse H; Department of Radiological Sciences, Ibaraki Prefectural University of Health Sciences, 4669-2, Ami, Inashiki, Ibaraki, 300-0394, Japan., Takaoka M; Master's Program in Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1, Tennoudai, Tsukuba, Ibaraki, 305-8577, Japan., Miyakawa S; Department of Radiological Sciences, Ibaraki Prefectural University of Health Sciences, 4669-2, Ami, Inashiki, Ibaraki, 300-0394, Japan., Koori N; Department of Radiological Sciences, Ibaraki Prefectural University of Health Sciences, 4669-2, Ami, Inashiki, Ibaraki, 300-0394, Japan., Takahashi M; Department of Radiological Sciences, Ibaraki Prefectural University of Health Sciences, 4669-2, Ami, Inashiki, Ibaraki, 300-0394, Japan., Shinoda K; Department of Radiation Technology, Ibaraki Prefectural Central Hospital, 6528, Koibuchi, Kasama, Ibaraki, 309-1793, Japan., Ikoma H; Department of Radiation Technology, Ibaraki Prefectural Central Hospital, 6528, Koibuchi, Kasama, Ibaraki, 309-1793, Japan., Fujisaki T; Department of Radiological Sciences, Ibaraki Prefectural University of Health Sciences, 4669-2, Ami, Inashiki, Ibaraki, 300-0394, Japan., Abe S; Department of Radiological Sciences, Ibaraki Prefectural University of Health Sciences, 4669-2, Ami, Inashiki, Ibaraki, 300-0394, Japan.
Jazyk: angličtina
Zdroj: Radiological physics and technology [Radiol Phys Technol] 2024 Oct 16. Date of Electronic Publication: 2024 Oct 16.
DOI: 10.1007/s12194-024-00850-6
Abstrakt: Patient respiration is characterized by respiratory parameters, such as cycle, amplitude, and baseline drift. In treatment planning using four-dimensional computed tomography (4DCT) images, the target dose may be affected by variations in image reconstruction techniques and respiratory parameters. This study aimed to optimize 4DCT image reconstruction techniques for the treatment planning of lung stereotactic body radiotherapy (SBRT) based on respiratory parameters using respiratory motion phantom. We quantified respiratory parameters using 30 respiratory motion datasets. The 4DCT images were acquired, and the phase- and amplitude-based reconstruction images (RI) were created. The target dose was calculated based on these reconstructed images. Statistical analysis was performed using Pearson's correlation coefficient (r) to determine the relationship between respiratory parameters and target dose in each reconstructed technique and respiratory region. In the inhalation region of phase-based RI, r of the target dose and baseline drift was -0.52. In particular, the target dose was significantly reduced for respiratory parameters with a baseline drift of 0.8 mm/s and above. No other respiratory parameters or respiratory regions were significantly correlated with target dose in phase-based RI. In amplitude-based RI, there were no significant differences in the correlation between all respiratory parameters and target dose in the exhalation or inhalation regions. These results showed that the target dose of the amplitude-based RI did not depend on changes in respiratory parameters or respiratory regions, compared to the phase-based RI. However, it is possible to guarantee the target dose by considering respiratory parameters during the inhalation region of the phase-based RI.
(© 2024. The Author(s), under exclusive licence to Japanese Society of Radiological Technology and Japan Society of Medical Physics.)
Databáze: MEDLINE
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