[Acquired hemophilia - quick diagnosis and treatment can significantly reduce the risk of mortality].

Autor: Johansson J; ST-läkare, barnmedicin, Drottning Silvias barnsjukhus, Göteborg., Söderberg M; med dr, överläkare, specialist i internmedicin, Södersjukhuset, Stockholm.
Jazyk: švédština
Zdroj: Lakartidningen [Lakartidningen] 2024 Oct 09; Vol. 121. Date of Electronic Publication: 2024 Oct 09.
Abstrakt: This case report of a 73-year-old male with bleedings provides insights into the clinical characteristics, diagnosis och treatment of acquired hemophilia A. It's a dangerous non-hereditary bleeding disorder caused by autoantibodies against coagulation factor VIII, often linked with other autoimmune diseases or malignancies, but it is also often idiopathic. The diagnosis remains a challenge due to its rarity and non-specific symtoms, but should be considered in unexplained bleeding cases with prolonged activated partial thromboplastin time (APTT). Quick  diagnosis and treatment can significantly reduce the risk of serious complications and mortality. The long-term prognosis usually depends on the presence of any underlying disease.
Databáze: MEDLINE