Contemporary surgical management of osteosarcoma and Ewing sarcoma.

Autor: Callan AK; Department of Orthopaedics, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Alexander JH; Department of Orthopaedics, The Ohio State University, Columbus, Ohio, USA., Montgomery NI; Department of Orthopaedics, Texas Children's Hospital, Houston, Texas, USA., Lindberg AW; Department of Orthopaedics, Seattle Children's Hospital, Seattle, Washington, USA., Scharschmidt TJ; Department of Orthopaedics, Nationwide Children's Hospital, Columbus, Ohio, USA., Binitie O; Department of Sarcoma, Moffitt Cancer Center, Tampa, Florida, USA.
Jazyk: angličtina
Zdroj: Pediatric blood & cancer [Pediatr Blood Cancer] 2024 Oct 15, pp. e31374. Date of Electronic Publication: 2024 Oct 15.
DOI: 10.1002/pbc.31374
Abstrakt: The incidence of malignant bone tumors has remained relatively stable over the past two decades between 8% and 9% per 1,000,000 in North America. Multidisciplinary treatment is paramount for optimal care combining surgical resection, chemotherapy, and rehabilitation. Surgical treatment aims for a negative margin resection of the sarcoma with a personalized reconstruction plan. Limb salvage surgery (LSS) is possible in the majority of cases; however, amputation (including rotationplasty) may be required or preferred. Reconstruction can be achieved utilizing endoprostheses, allograft, autograft, or a combination of these techniques. Emerging technologies such as 3D printing of implants and cutting guides, and intraoperative navigation have helped to improve options for LSS.
(© 2024 Wiley Periodicals LLC.)
Databáze: MEDLINE
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