Implementation of spirometry screening for post-tuberculosis lung disease (PTLD) among adolescents and adults enrolled within the National Tuberculosis Control Program of Carmelo Hospital in Chókwè District, Mozambique: A hybrid type III effectiveness-implementation study protocol.

Autor: Myers H; Department of Tropical Medicine and Infectious Diseases, Celia Scott Weatherhead School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA., Chongo B; Department of Medicine, Daughters of Charity, Saint Vincent de Paul, Carmelo Hospital of Chókwè, Chókwè District, Gaza Province, Mozambique., Zifodya JS; Section of Pulmonary Critical Care and Environmental Medicine, Department of Internal Medicine, Tulane University School of Medicine, New Orleans, LA, USA., Zacaria I; Department of Medicine, Daughters of Charity, Saint Vincent de Paul, Carmelo Hospital of Chókwè, Chókwè District, Gaza Province, Mozambique., Machava E; Department of Medicine, Daughters of Charity, Saint Vincent de Paul, Carmelo Hospital of Chókwè, Chókwè District, Gaza Province, Mozambique., Simango A; Department of Medicine, Daughters of Charity, Saint Vincent de Paul, Carmelo Hospital of Chókwè, Chókwè District, Gaza Province, Mozambique., Amorim G; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Mavume-Mangunyane E; Fundação Aurum Moçambique, Maputo, Mozambique., Chiau R; Fundação Aurum Moçambique, Maputo, Mozambique., Kampa KT; Department of Tropical Medicine and Infectious Diseases, Celia Scott Weatherhead School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA., Madede T; Faculty of Medicine, University Eduardo Mondlane, Maputo, Mozambique., Sidat M; Faculty of Medicine, University Eduardo Mondlane, Maputo, Mozambique., Moon TD; Department of Tropical Medicine and Infectious Diseases, Celia Scott Weatherhead School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA. tmoon2@tulane.edu.
Jazyk: angličtina
Zdroj: BMC pulmonary medicine [BMC Pulm Med] 2024 Oct 10; Vol. 24 (1), pp. 502. Date of Electronic Publication: 2024 Oct 10.
DOI: 10.1186/s12890-024-03329-7
Abstrakt: Background: Despite receiving adequate treatment, many tuberculosis (TB) survivors are left with post-tuberculosis complications, possibly due to lung tissue damage incurred during the active period of the disease. Current TB programs worldwide deliver quality care throughout the course of active TB treatment, yet often fail to provide organized follow-up once treatment ends. Post-tuberculosis lung disease (PTLD) is a prominent, yet underrecognized cause of chronic lung disease, managed similarly to chronic respiratory diseases with pharmacotherapy and/or personalized pulmonary rehabilitation interventions. Basic pulmonary rehabilitation packages for people finishing TB treatment are still lacking in low- and middle-income countries (LMICs). We offer a study protocol to evaluate the implementation of spirometry and symptom screening for PTLD among people who have completed TB treatment in a rural district in Mozambique.
Methods: The overall objective of this study is to evaluate the introduction of a new screening program that utilizes symptom screening and spirometry for diagnosing PTLD among adolescents and adults that have completed TB treatment. This research protocol consists of three complementary components: 1) assessing the prevalence of PTLD among patients enrolled in the National TB Control Program (NTCP) at Carmelo Hospital (CHC) in Chókwè District, Mozambique; 2) evaluating anticipated implementation outcomes through the identification of the site-, provider-, and individual-level determinants that either facilitate or hinder the successful adoption, implementation, and maintenance of the spirometry screening program, and 3) evaluating the real-time implementation outcomes/processes in order to provide practical evidence-based key indicators of successful implementation of the spirometry screening program.
Discussion: Providing well-organized, evidence-based care for individuals with a history of TB who are experiencing symptoms of PTLD can relieve chronic respiratory issues, enhance quality of life, and potentially lower the risk of further pulmonary infections, including recurrent TB. However, there is a significant gap in the literature regarding the implementation of best practices of HIV and TB health services delivery. Addressing this gap could assist Mozambique in improving diagnosis, treatment, and continuity of care for people formerly living with TB. The insights from this study will help decision-makers improve spirometry screening coverage, enhance intervention effectiveness, and translate our findings to evidence-based programming.
Trial Registration: ISRCTN92021748 retrospectively registered.
(© 2024. The Author(s).)
Databáze: MEDLINE
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