Conchocarpus J. C. Mikan (Rutaceae): Chemical Constituents and Biological Activities.

Autor: Santos AR; Department of Chemistry, Universiade Federal de Minas Gerais, Av. Pres. Antonio Carlos, 6627, Campus Pampulha, CEP 31270-901, Belo Horizonte, MG, Brasil., de Paula VF; Department of Science and Technology, Universidade Estadual do Sudoeste da Bahia, Av. José Moreira Sobrinho, s/n, CEP 45208-091, Jequié, Bahia, Brazil., Barbosa LCA; Department of Chemistry, Universiade Federal de Minas Gerais, Av. Pres. Antonio Carlos, 6627, Campus Pampulha, CEP 31270-901, Belo Horizonte, MG, Brasil.
Jazyk: angličtina
Zdroj: Chemistry & biodiversity [Chem Biodivers] 2024 Oct 08, pp. e202402119. Date of Electronic Publication: 2024 Oct 08.
DOI: 10.1002/cbdv.202402119
Abstrakt: Rutaceae Juss. stands out as a botanical family recognized for its remarkable diversity in taxonomy, worldwide distribution, chemical composition, and biological activity exhibited by its compounds. Conchocarpus J. C. Mikan is one of the main genera of this family, comprising 50 species distributed throughout the Neotropical America. Brazil is the main center of diversity for this genus, hosting 66 % of the species as endemic. This is the first review concerning the genus Conchocarpus, emphasizing its chemical composition and biological activities. The selected papers for this review cover studies on 11 species, of which were identified 88 compounds. Among these, quinoline and acridone alkaloids predominate (57 %), followed by flavonoids, amides, coumarins and terpenoids. The biological activities of extracts and compounds indicate trypanocidal and leishmanicidal actions, as well as cytotoxic, fungicidal, molluscicidal, insecticidal, anticholinesterase and antioxidant activities.
(© 2024 Wiley-VHCA AG, Zurich, Switzerland.)
Databáze: MEDLINE
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