Magnetic solid-phase extraction of amoxicillin and doxycycline from water and urine samples based on cetylpyridinium chloride-modified Fe 3 O 4 nanoparticles followed by spectrophotometric determination.

Autor: Mohammed T; Department of Chemistry, College of Science, University of Baghdad, Baghdad, Iraq., Hadi H; Department of Chemistry, College of Science, University of Baghdad, Baghdad, Iraq. hind.h@sc.uobaghdad.edu.iq.
Jazyk: angličtina
Zdroj: Environmental monitoring and assessment [Environ Monit Assess] 2024 Sep 30; Vol. 196 (10), pp. 990. Date of Electronic Publication: 2024 Sep 30.
DOI: 10.1007/s10661-024-13185-x
Abstrakt: This research describes an easy, rapid, and inexpensive magnetic solid-phase extraction (MSPE) approach employing Fe 3 O 4 magnetic nanoparticles modified with cetylpyridinium chloride (Fe 3 O 4 @CPC/MNPs) for extracting amoxicillin (AMX) and doxycycline (DOX) after derivatization with 4-chloroaniline as a color reagent. The azo-coupling of AMX and DOX with the color reagent in the alkaline medium caused yellow and yellow-orange azo dyes with maximum absorption wavelengths of 435 and 438 nm, respectively. The UV-Vis spectroscopy was utilized to determine the target analyte after the extraction procedure. Good linearities (R 2  > 0.99) in the concentration ranges of 0.03-4.50 and 0.05-6.00 µg/mL were obtained for AMX and DOX, respectively. The experimental detection limits of AMX and DOX were obtained as 0.01 and 0.02 µg/mL, respectively. The developed approach was effectively applied to pre-concentrate and quantify AMX and DOX in environmental water and urine samples.
(© 2024. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)
Databáze: MEDLINE
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