Evaluation of Prevention of Initial Enamel Lesions around Orthodontic Brackets by Using Different Remineralizing Agents: An Original Research.

Autor:	Pavethynath V; Department of Orthodontic Science, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan., Rathore BS; Department of Orthodontics and Dentofacial Orthopaedics, College of Dental Science and Hospital Rau, Indore, Madhya Pradesh, India., Krishna NM; Department of Orthodontics, Priyadarshini Dental College and Hospital, Pandur, Tamil Nadu, India., Pragnya B; Department of Orthodontics, Mamata Dental College, Khammam, Telangana, India., Menon I; Professor & Head, Department of Public Health Dentistry, Kalinga Institute of Dental Sciences, KIIT Deemed to be University, Bhubneswar, Odisha, India., Varma Datla PK; Department of Orthodontics, Vishnu Dental College, Vishnupur, Bhimavaram, Andhra Pradesh, India., Pujari PR; BDS, SMBT Dental College and Hospital, Amrutnagar Ghulewadi, Sangamner, Maharashtra, India.
Jazyk:	angličtina
Zdroj:	Journal of pharmacy & bioallied sciences [J Pharm Bioallied Sci] 2024 Jul; Vol. 16 (Suppl 3), pp. S2605-S2607. Date of Electronic Publication: 2024 Jul 01.
DOI:	10.4103/jpbs.jpbs_397_24
Abstrakt:	Objective: The purpose of this study was to compare the efficacy of various remineralizing agents in stopping the early enamel lesions surrounding orthodontic brackets from progressing. Techniques: Four groups were randomly allocated to a total of 100 participants: the control group (no treatment), calcium phosphate, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), and fluoride varnish. Remineralizing chemicals were administered in accordance with manufacturer recommendations, and enamel lesions were created around orthodontic brackets. At baseline and follow-up visits, enamel lesion development was evaluated by visual inspection, quantitative light-induced fluorescence, and microhardness tests. Results: All treatment groups showed significant improvements in microhardness and decreases in lesion size compared to the control group ( P < 0.05). Of all the treatment groups, CPP-ACP showed the most notable improvement in microhardness. Regarding the reduction of lesion size, there were no notable variations between the therapy groups ( P > 0.05). Conclusion: Initial enamel lesions surrounding orthodontic brackets can be effectively prevented from progressing with the use of fluoride varnish, calcium phosphate, and CPP-ACP. Promising improvements in microhardness indicate that CPP-ACP may be a better treatment choice. Larger sample sizes and longer follow-up times are needed for future studies to validate these results and clarify the best strategy for maintaining the health of enamel throughout orthodontic treatment. Competing Interests: There are no conflicts of interest. (Copyright: © 2024 Journal of Pharmacy and Bioallied Sciences.)
Databáze:	MEDLINE
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