Euterpe Oleracea Martius (Açaí) Extract and Resistance Exercise Modulate Cardiac Parameters of Hypertensive Rats.

Autor: de Meireles PB; Department of Physical Education and Nutrition, Governador Ozanam Coelho University Center, Ubá 36506-022, MG, Brazil., de Miranda DC; Department of Physical Education and Nutrition, Governador Ozanam Coelho University Center, Ubá 36506-022, MG, Brazil., de Moura AG; Department of Physical Education and Nutrition, Governador Ozanam Coelho University Center, Ubá 36506-022, MG, Brazil., Ribeiro WC; Department of Physical Education and Nutrition, Governador Ozanam Coelho University Center, Ubá 36506-022, MG, Brazil., Oliveira ÂQ; Department of Physical Education and Nutrition, Governador Ozanam Coelho University Center, Ubá 36506-022, MG, Brazil., Leite LB; Laboratory of Exercise Biology, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil.; Department of Sports, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal., Forte P; Department of Sports, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal.; Department of Sports, Higher Institute of Educational Sciences of the Douro, 4560-708 Penafiel, Portugal.; CI-ISCE, ISCE Douro, 4560-547 Penafiel, Portugal.; Research Center for Active Living and Wellbeing (LiveWell), Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal., Ribeiro L; Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Alameda Santa Apolónia, 5300-253 Bragança, Portugal.; Laboratório Associado para a Sustentabilidade e Tecnologia em Regiões de Montanha (SusTEC), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.; Facultade de Ciencias, Universidad de Vigo, 32004 Ourense, Spain., Encarnação SG; Department of Sports, Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal.; Department of Sports, Higher Institute of Educational Sciences of the Douro, 4560-708 Penafiel, Portugal.; CI-ISCE, ISCE Douro, 4560-547 Penafiel, Portugal.; Research Center for Active Living and Wellbeing (LiveWell), Instituto Politécnico de Bragança, 5300-253 Bragança, Portugal.; Department of Physical Education, Sport and Human Movement, Universidad Autónoma de Madrid (UAM), Ciudad Universitaria de Cantoblanco, 28049 Madrid, Spain., Guimarães-Ervilha LO; Departament of Biological Sciences, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil., Machado-Neves M; Departament of Biological Sciences, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil., E Dias MM; Department of Nutrition and Health, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil., Campos IX; Department of Nutrition and Health, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil., Reis ECC; Department of Veterinary Medicine, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil., Peluzio MDCG; Department of Nutrition and Health, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil., Natali AJ; Laboratory of Exercise Biology, Federal University of Viçosa, Viçosa 36590-000, MG, Brazil., Lavorato VN; Department of Physical Education and Nutrition, Governador Ozanam Coelho University Center, Ubá 36506-022, MG, Brazil.
Jazyk: angličtina
Zdroj: Life (Basel, Switzerland) [Life (Basel)] 2024 Sep 02; Vol. 14 (9). Date of Electronic Publication: 2024 Sep 02.
DOI: 10.3390/life14091101
Abstrakt: Background: The study evaluated the effects of resistance exercise training and açaí supplementation on cardiac parameters in hypertensive animals.
Methods: For this study, rats from the Wistar and SHR lines (spontaneously hypertensive rats) were used. The animals were divided into 5 groups: Wistar Control (C); Control Hypertensive (H); Trained Hypertensive (HT); Hypertensive and Supplemented with Açaí (HA); and Hypertensive Trained and Supplemented with Açaí (HAT). Resistance exercise training was carried out through climbing. The supplemented groups received 3 g of açaí/kg of body mass. The animals' systolic blood pressure (SBP), body mass, and physical test were measured at the beginning and end of the intervention. At the end, an echocardiographic analysis was performed. Histological analysis and oxidative stress of the LV were performed.
Results: It was found that hypertensive animals showed an increase in SBP, and the treatments reduced this parameter. The trained groups achieved higher values of maximum carrying load. Hypertension increased the dimension of the left ventricular free wall in diastole and reduced ejection and shortening fractions. The trained groups showed improvement in ejection and shortening fractions. The H group increased the proportion of extracellular matrix and reduced the proportion of cells, with the HAT group attenuating this change. Cell diameter was greater in group H, and all treatments reduced this parameter. Hypertension increased the concentration of malondialdehyde and decreased catalase activity in LV. The treatments managed to mitigate this damage.
Conclusions: It is concluded that the treatments managed to generate positive cardiovascular adaptations, and their combination enhanced these effects.
Databáze: MEDLINE
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