Pulsatile Left Ventricular Assistance in High-Risk Percutaneous Coronary Interventions: Short-Term Outcomes.

Autor: Bulum J; Department of Internal Medicine, University Hospital Center Zagreb, 10000 Zagreb, Croatia., Bastos MB; Thoraxcentrum, Erasmus Medical Center, 3015 GD Rotterdam, The Netherlands., Hlinomaz O; Department of Cardiology, International Clinical Research Center, St. Anne University Hospital and Masaryk, University School of Medicine, 656 91 Brno, Czech Republic., Malkin O; PulseCath BV, 6811 KS Arnhem, The Netherlands., Pawlowski T; Department of Cardiology, National Institute of Medicine, 02-507 Warsaw, Poland., Dragula M; Department of Cardiology, University Hospital in Martin, 036 01 Martin, Slovakia., Gil R; Department of Cardiology, National Medical Institute of the Internal Affairs and Administration Ministry, 02-005 Warsaw, Poland.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2024 Sep 10; Vol. 13 (18). Date of Electronic Publication: 2024 Sep 10.
DOI: 10.3390/jcm13185357
Abstrakt: Objectives: To document the real-world experience with the use of pneumatic pulsatile mechanical circulatory support (MCS) with the PulseCath iVAC2L during high-risk percutaneous coronary interventions (HR-PCIs). Background : The use of MCS in HR-PCIs may reduce the rate of major adverse cardiovascular events (MACEs) at 90 days. The PulseCath iVAC2L is a short-term pulsatile transaortic left ventricular (LV) assist device that has been in use since 2014. The iVAC2L Registry tracks its safety and efficacy in a variety of hospitals worldwide. Methods : The iVAC2L Registry is a multicenter, observational registry that aggregates clinical data from patients treated with the iVAC2L worldwide. A total of 293 consecutive cases were retrospectively collected and analyzed. Estimated rates of in-hospital clinical endpoints were described. All-cause mortality was used as the primary endpoint and other outcomes of interest were used as secondary endpoints. The rates obtained were reported and contextualized. Results : The in-hospital rate of all-cause mortality was 1.0%, MACE was 3.1%. Severe hypotension occurred in 8.9% of patients. Major bleeding and major vascular complications occurred in 1.0% and 2.1%, respectively. Acute myocardial infarction occurred in 0.7% of patients. Cerebrovascular events occurred in 1.4% of patients. Cardiac arrest occurred in 1.7% of patients. A statistically significant improvement in blood pressure was observed with iVAC2L activation. Conclusions : The results of the present study suggest that the iVAC2L is capable of improving hemodynamics with a low rate of adverse events. However, confirmatory studies are needed to validate these findings.
Databáze: MEDLINE
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