| Autor: |
Nica S; Emergency Discipline, University Hospital of Bucharest, 050098 Bucharest, Romania.; Department of Emergency and First Aid, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania., Nica RI; Central Military Emergency University Hospital 'Dr. Carol Davila', 010825 Bucharest, Romania.; Discipline of General Surgery, Faculty of Midwifery and Nursing, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania., Nica HA; Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd., 050474 Bucharest, Romania., Miricescu D; Discipline of Biochemistry, Faculty of Dentistry, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania., Abdelfatah MAAK; Central Military Emergency University Hospital 'Dr. Carol Davila', 010825 Bucharest, Romania., Schiopu OM; Central Military Emergency University Hospital 'Dr. Carol Davila', 010825 Bucharest, Romania., Nedelcu IC; Central Military Emergency University Hospital 'Dr. Carol Davila', 010825 Bucharest, Romania., Cimponeriu DG; Discipline of Genetics, Faculty of Biology, University of Bucharest, 010041 Bucharest, Romania., Stefani C; Department I of Family Medicine and Clinical Base, 'Dr. Carol Davila' Central Military Emergency University Hospital, 051075 Bucharest, Romania., Stanescu-Spinu II; Discipline of Physiology, Faculty of Dentistry, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd, 050474 Bucharest, Romania., Ciornei MC; Emergency Discipline, University Hospital of Bucharest, 050098 Bucharest, Romania.; Discipline of Physiology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania. |
| Abstrakt: |
Background: This retrospective study aimed to evaluate the characteristics of patients with long COVID syndrome. Methods: This study included 457 adults who had at least one persistent symptom after COVID-19 infection. Results: The median time interval between the last SARS-CoV-2 infection and emergency room presentation was 3 months. Older patients had comorbidities (61.7 vs. 44.9 years, p < 0.0001), moderate or severe forms of COVID-19 (61.2 vs. 50.9 years, p < 0.0001), and respiratory symptoms (56.1 vs. 52.0 years, p = 0.0027). Non-vaccinated patients were older than vaccinated patients (56.0 vs. 51.5 years, p = 0.0008) and had residual lung abnormalities following COVID-19 infection (51.5% vs. 36.8%, p < 0.003). The time interval between the last SARS-CoV-2 infection and the hospital evaluation was shorter for vaccinated patients (3.2 vs. 3.9 months, p < 0.0001) and those with mild forms (3.3 vs. 4.12 months, p = 0.0001) versus non-vaccinated individuals. After the last SARS-CoV-2 infection, 107 patients developed impaired fasting glucose, impaired glucose tolerance, or diabetes mellitus, being patients with already known chronic diseases ( p = 0.0002), or hypertension ( p = 0.001). Conclusions: Our study pointed out the heterogeneity of symptoms following COVID-19, and they are associated with age, vaccination status, or severity of SARS-CoV-2 infection. |
