| Autor: |
Scriffignano S; Academic Rheumatology Unit, Department of Medicine and Health Science 'Vincenzo Tiberio,' University of Molise, Campobasso., Perrotta FM; Academic Rheumatology Unit, Department of Medicine and Health Science 'Vincenzo Tiberio,' University of Molise, Campobasso., Ricci M; Nuclear Medicine Unit, Ospedale Cardarelli, Campobasso., Carabellese B; Nuclear Medicine Unit, Ospedale Cardarelli, Campobasso., Lubrano E; Academic Rheumatology Unit, Department of Medicine and Health Science 'Vincenzo Tiberio,' University of Molise, Campobasso. |
| Jazyk: |
angličtina |
| Zdroj: |
Reumatismo [Reumatismo] 2024 Sep 24. Date of Electronic Publication: 2024 Sep 24. |
| DOI: |
10.4081/reumatismo.2024.1647 |
| Abstrakt: |
Visceral muscle dysmotility syndrome (VMDS) is a rare syndrome, described in the systemic lupus erythematosus (SLE) clinical course. It is characterized by diffuse thickened intestinal wall and gastrointestinal-genitourinary-hepatobiliary hollow viscera dilatation and dysmotility. Due to the rarity and the heterogeneity of the clinical characteristics of this syndrome, it is not entirely clear which is the best diagnostic imaging technique for the diagnosis and/or follow-up, even if, in all the described cases, computed tomography (CT) was generally used to study visceral involvement. However, there are no cases describing the visceral metabolic activity by 18 fluorodeoxyglucose (18FDG)-positron emission tomography-CT (18FDG-PET-CT). Here, we reported the first clinical case of VMDS studied by 18FDG-PET-CT, characterizing the metabolic activity of this rare syndrome during SLE flare. We found a high intestinal metabolic burden, hyper-fixation in duodenum, and high hepatic metabolic activity. Moreover, we reviewed the literature on VMDS in SLE, focusing on imaging techniques in different anatomical sites (bowel, urinary tract, bile ducts), patients' symptoms, and treatment. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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