Do patients infected with human coronavirus before the COVID-19 pandemic have less risk of being infected with COVID-19?

Autor:	Şanlidağ Işbilen G; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, İzmir, Turkiye., Uysal AA; Department of Medical Microbiology, Faculty of Medicine, Ege University, İzmir, Turkiye., Yiğit S; Department of Medical Microbiology, School of Medicine, Division of Medical Virology, Gazi University, Ankara, Turkiye., Appak Ö; Department of Medical Microbiology, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkiye., Sipahi H; Bornova Directorate of Health, İzmir, Turkiye., Bozdayi G; Department of Medical Microbiology, School of Medicine, Division of Medical Virology, Gazi University, Ankara, Turkiye., Sayiner A; Department of Medical Microbiology, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkiye., Çiçek C; Department of Medical Microbiology, Faculty of Medicine, Ege University, İzmir, Turkiye., Güzel Tunçcan Ö; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Gazi University, Ankara, Turkiye., Sipahi OR; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Ege University, İzmir, Turkiye.; King Hamad University Hospital, Bahrain Oncology Center, Department of Infectious Diseases, Al Muharraq, Bahrain.
Jazyk:	angličtina
Zdroj:	Turkish journal of medical sciences [Turk J Med Sci] 2024 Mar 11; Vol. 54 (4), pp. 761-765. Date of Electronic Publication: 2024 Mar 11 (Print Publication: 2024).
DOI:	10.55730/1300-0144.5846
Abstrakt:	Background/aim: Although seasonal human coronaviruses (HCoVs) have long been recognized as respiratory tract viruses, the newly identified SARS-CoV-2 caused a pandemic associated with severe respiratory failure. We aimed to evaluate the incidence of COVID-19 infection in patients diagnosed in three tertiary teaching hospitals, both with and without prior confirmed HCoV infection, and to compare these cohorts in terms of COVID-19 contraction. Materials and Methods: In our study, we examined HCoV PCR-positive cases obtained retrospectively between January 2014 and March 2020 from three University Hospital Microbiology Laboratories (Cohort 1), as well as PCR-negative patients detected in the same PCR cycle as the positive cases (Cohort 2). We also evaluated subgroups of HCoV-positive cases. Results: There was no difference in COVID-19 contraction rates between Cohort 1 and Cohort 2 (p = 0.724). When previous HCoV subgroups of COVID-19-positive patients were examined, no significant difference was found between the betacoronavirus and alphacoronavirus subgroups (p = 0.822), among the four groups (NL63, 229E, OC43, HKU-1) (p = 0.207), or between the OC43 subgroup and the other groups (p = 0.295). Conclusion: Being previously infected with HCoV did not provide protection against COVID-19 in our study group. We suggest evaluating the possible effect of previous OC43 infection on COVID-19 contraction in larger cohorts. Competing Interests: Conflict of interest: The authors declare that they have no competing interests. (© TÜBİTAK.)
Databáze:	MEDLINE
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