The Intersection of Socioeconomic Differences and Sex in the Management and Outcomes of Acute Myocardial Infarction: A Nationwide Cohort Study.

Autor: Weight N; Keele Cardiovascular Research Group, Centre for Prognosis Research, Institute for Primary Care and Health Sciences, Keele University, Keele, UK., Moledina S; Keele Cardiovascular Research Group, Centre for Prognosis Research, Institute for Primary Care and Health Sciences, Keele University, Keele, UK., Lawson CA; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK., Van Spall HGC; Department of Medicine and Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.; Population Health Research Institute, Research Institute of St Joe's, Hamilton, ON, Canada., Wijeysundera HC; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.; Institute for Clinical Evaluative Sciences, Toronto, Canada.; Schulich Heart Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, Canada., Rashid M; Keele Cardiovascular Research Group, Centre for Prognosis Research, Institute for Primary Care and Health Sciences, Keele University, Keele, UK.; Department of Cardiovascular Sciences, Glenfield Hospital, University Hospitals of Leicester NHS Trust Leicester United Kingdom.; NIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK., Kontopantelis E; Division of Informatics, Imaging and Data Sciences, University of Manchester, Manchester, UK., Mamas MA; Keele Cardiovascular Research Group, Centre for Prognosis Research, Institute for Primary Care and Health Sciences, Keele University, Keele, UK.; National Institute for Health and Care Research (NIHR) Birmingham Biomedical Research Centre, UK.
Jazyk: angličtina
Zdroj: Angiology [Angiology] 2024 Sep 19, pp. 33197241273433. Date of Electronic Publication: 2024 Sep 19.
DOI: 10.1177/00033197241273433
Abstrakt: Patients with lower socioeconomic status (SES) have poorer outcomes following acute myocardial infarction (AMI) than patients with higher SES; however, how sex modifies socioeconomic differences is unclear. Using the United Kingdom (UK) Myocardial Ischaemia National Audit Project (MINAP) registry, alongside Office of National Statistics (ONS) mortality data, we analyzed 736,420 AMI patients between 2005 and 2018, stratified by Index of Multiple Deprivation (IMD) score Quintiles (most affluent [Q1] to most deprived [Q5]). There was no significant difference in probability of in-hospital mortality in our adjusted model according to sex. The probability of 30-day mortality in our adjusted model was similar between men and women throughout Quintiles, ((Q5; Men 7.6%; 95% CI 7.3-7.8% ( P < .001), Women; 7.0%; 95% CI 6.8-7.3%, P < .001)) ((Q1; Men 7.1%; 95% CI 6.8-7.4%, P < .001, Women; 6.9%; 95% CI 6.6-7.1%, P < .001)). The probability of one-year mortality in our adjusted model was higher in men throughout all Quintiles (Q1; Men 15.0%; 95% CI 14.8-15.6%), P < .001, Women; 14.5%; 95% CI 14.2-14.9%, P < .001) (Q5; Men 16.9%; 95% CI 16.5-17.3%, P < .001, Women; 15.5%; 95% CI 15.1-15.9 by %, P < .001). Overall, female sex did not significantly influence the effect of deprivation on AMI processes of care and outcomes.
Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze: MEDLINE