| Autor: |
Aounallah A; Department of Dermatology, Farhat Hached Hospital, Sousse, Tunisia., Saad S; Department of Dermatology, Farhat Hached Hospital, Sousse, Tunisia; drsaadsarra@gmail.com., Ghariani Fetoui N; Department of Dermatology, Farhat Hached Hospital, Sousse, Tunisia., Denguezli M; Department of Dermatology, Farhat Hached Hospital, Sousse, Tunisia. |
| Jazyk: |
angličtina |
| Zdroj: |
Skinmed [Skinmed] 2024 Sep 17; Vol. 22 (4), pp. 272-275. Date of Electronic Publication: 2024 Sep 17 (Print Publication: 2024). |
| Abstrakt: |
Juvenile dermatomyositis (JDM) is the leading cause of chronic idiopathic inflammatory myopathy of auto-immune origin in children. Seven patients with JDM found in the records from 1998-2019 of the Department of Dermatology Farhat Hached Hospital, Sousse, Tunisia. Our study concerned a total of six girls and one boy with a median age at disease onset of 8,16 years. The average time before diagnosis was 8,8 months. The onset of the disease was acute in 2 patients. All patients displayed skin manifestations at diagnosis, with proximal muscular weakness in 4 cases. Four patients had elevated muscle enzymes and all of them showed myopathic findings on electromyography. Oral corticosteroids were prescribed in 6 patients, in association with other systemic therapies. Three patients achieved a good outcome while two others relapsed. The two other patients showed corticosteroids resistance with a fatal outcome in one case. This study highlights the diagnostic features and management of juvenile dermatomyositis. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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