| Autor: |
Samuelsson JG; Massachusetts General Hospital - Massachusetts Institute of Technology - Harvard Medical School Harvard-MIT Division of Health Sciences and Technology.; Athinoula A. Martinos Center for Biomedical Imaging, 149 13th St., Charlestown, MA 02129, USA., Schmahmann JD; Ataxia Center, Cognitive Behavioral Neurology Unit, Laboratory for Neuroanatomy and Cerebellar Neurobiology, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Sereno M; Psychology Department, San Diego State University and Cognitive Science Department, University of California San Diego, San Diego, CA., Rosen B; Massachusetts General Hospital - Massachusetts Institute of Technology - Harvard Medical School Harvard-MIT Division of Health Sciences and Technology.; Athinoula A. Martinos Center for Biomedical Imaging, 149 13th St., Charlestown, MA 02129, USA., Hämäläinen MS; Massachusetts General Hospital - Massachusetts Institute of Technology - Harvard Medical School Harvard-MIT Division of Health Sciences and Technology.; Athinoula A. Martinos Center for Biomedical Imaging, 149 13th St., Charlestown, MA 02129, USA.; Department of Neuroscience and Biomedical Engineering, School of Science, Aalto University, 02150 Espoo, Finland. |
| Abstrakt: |
Scientific interest in the cerebellum has surged in the last few decades with an emerging consensus on a multifaceted functionality and intricate, but not yet fully understood, functional topography over the cerebellar cortex. To further refine this structure-function relationship and quantify its inter-subject variability, a high-resolution digital anatomical atlas is fundamental. Using a combination of manual labeling and image processing, we turned a recently published reconstruction of the human cerebellum, the first such reconstruction fine enough to resolve the individual folia, into a digital atlas with both surface and volumetric representations. Its unprecedented granularity (0.16 mm) and detailed expert labeling make the atlas usable as an anatomical ground truth, enabling new ways of analyzing and visualizing cerebellar data through its digital format. |
