The Role of Diffusion-Weighted Imaging in Characterizing Benign and Malignant Breast Lesions: A Retrospective Study.
| Autor: | Jerosha S; Radiodiagnosis, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND., Subramonian SG; Radiodiagnosis, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND., Mohanakrishnan A; Radiodiagnosis, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND., Ramakrishnan KK; Radiodiagnosis, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND., Natarajan P; Radiodiagnosis, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Aug 08; Vol. 16 (8), pp. e66472. Date of Electronic Publication: 2024 Aug 08 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.66472 |
| Abstrakt: | Introduction Diffusion-weighted imaging (DWI) is a promising magnetic resonance imaging (MRI) technique for differentiating between benign and malignant breast lesions. This study set out to assess the diagnostic utility of DWI and apparent diffusion coefficient (ADC) values in the characterization of breast lesions. Materials and methods A retrospective analysis comprised 30 patients with breast lesions who had breast MRI with DWI. The histopathological findings, ADC readings, and conventional MRI features were all analyzed. The receiver operating characteristic (ROC) curve analysis method was utilized to assess the diagnostic accuracy of DWI. Results Out of the 30 lesions, 22 (73.3%) were benign and eight (26.7%) were malignant. Malignant lesions exhibited significantly lower ADC values (p < 0.001) compared to benign lesions. An ADC cutoff value of 1.1 × 10 -3 mm 2 /s was optimal for differentiating benign from malignant lesions, yielding 90.81% sensitivity, 91.51% specificity, and 91.5% accuracy. Conclusion Combining DWI with quantitative ADC analysis is a helpful, non-invasive method for the characterization of breast lesions. It shows excellent diagnostic accuracy in identifying benign and malignant lesions, which may cut down on pointless biopsies and help with patient management. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Jerosha et al.) |
| Databáze: | MEDLINE |
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