The effectiveness of intravenous zoledronic acid in elderly patients with osteoporosis after rotator cuff repair: a retrospective study.

Autor: Zhao Y; Centre of Orthopaedics, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, Shaanxi Province, People's Republic of China., Shang D; Centre of Orthopaedics, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, Shaanxi Province, People's Republic of China., Zhang Y; Centre of Orthopaedics, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, Shaanxi Province, People's Republic of China., Geng Z; Centre of Orthopaedics, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, Shaanxi Province, People's Republic of China., Li D; Centre of Orthopaedics, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, Shaanxi Province, People's Republic of China., Song Q; Centre of Orthopaedics, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, Shaanxi Province, People's Republic of China., Wang J; Department of Orthopaedics, Xi'an No. 3 Hospital, The Affiliated Hospital of Northwest University, Xi'an, 710004, Shaanxi Province, People's Republic of China., Fu Z; Department of Orthopaedics, Xi'an No. 3 Hospital, The Affiliated Hospital of Northwest University, Xi'an, 710004, Shaanxi Province, People's Republic of China., Shi Z; Centre of Orthopaedics, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, Shaanxi Province, People's Republic of China., Fan L; Centre of Orthopaedics, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xiwu Road, Xi'an, 710004, Shaanxi Province, People's Republic of China. drfanlf@163.com.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2024 Sep 08; Vol. 14 (1), pp. 20891. Date of Electronic Publication: 2024 Sep 08.
DOI: 10.1038/s41598-024-68246-5
Abstrakt: The aim of this study was to investigate the effect of zoledronic acid (ZA) on postoperative healing and functional rehabilitation in osteoporotic patients with rotator cuff (RC) injury. 96 Patients were divided into three groups according to bone mineral density and ZA use (Group A: normal BMD; Group B: osteoporosis and intravenous ZA use; Group C: osteoporosis, without ZA use). Radiologic, functional and Serological outcomes were evaluated 6 months after surgery. The functional scores in all groups exhibited significant improvement 6 months after surgery. Inter-group comparison showed that Constant Shoulder joint function Score (CSS) of group A not significantly differing from that of group B, the other indicators were significantly better than those of group B and C. There were no significant differences in shoulder forward flexion, abductive Range of Motion between group B and C. Other indicators of group B were significantly improved compared to group C. The retear rate in group C (30.3%, 10/33) was higher than group A (6.1%, 2/33) and group B (13.3%, 4/30). In conclusion, the application of ZA can significantly reduce the rate of RC retear in elderly patients with osteoporosis after surgery, which is significant for postoperative shoulder joint functional rehabilitation.
(© 2024. The Author(s).)
Databáze: MEDLINE
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