Endoscopic Diagnosis of Primary Intestinal Lymphangiectasia in an Adult With Refractory Protein-Losing Enteropathy: A Case Report.
| Autor: | Khalil Z; College of Medicine, October 6 University, Cairo, EGY., Ali HN; College of Medicine, October 6 University, Cairo, EGY., Ibrahim H; College of Medicine, October 6 University, Cairo, EGY., Al-Abbedien EZ; Geriatrics, Beni Suef Hospital, Beni Suef, EGY. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Aug 04; Vol. 16 (8), pp. e66141. Date of Electronic Publication: 2024 Aug 04 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.66141 |
| Abstrakt: | Primary intestinal lymphangiectasia (PIL) is a rare disorder characterized by dilated lymphatic vessels in the gastrointestinal tract, leading to protein-losing enteropathy (PLE). We report the case of a 43-year-old male presenting with refractory PLE, characterized by generalized edema, chronic diarrhea, and significant weight loss over four months. Despite multiple consultations and treatments for presumed inflammatory bowel disease, his symptoms persisted, and his condition worsened. An upper endoscopy was performed, revealing white villi in the duodenum. Histopathological examination of duodenal biopsies confirmed the presence of markedly dilated lymphatic vessels in the lamina propria, consistent with PIL. The patient was managed with a high-protein, low-fat diet supplemented with medium-chain triglycerides (MCTs) and octreotide therapy. This treatment regimen led to significant clinical improvement, including reduced edema, normalization of albumin levels, and resolution of gastrointestinal symptoms. This case underscores the importance of considering PIL in adults with refractory PLE. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Review Board of October 6 University issued approval IRB-2024-0164. All procedures performed or images taken were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Khalil et al.) |
| Databáze: | MEDLINE |
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