Geriatric assessment for the practicing clinician: The why, what, and how.

Autor: Magnuson A; Division of Hematology/Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA., Loh KP; Division of Hematology/Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA., Stauffer F; Division of Hematology/Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA., Dale W; Department of Supportive Care, City of Hope, Antelope Valley, Duarte, California, USA., Gilmore N; Division of Supportive Care in Cancer, Department of Surgery, University of Rochester Medical Center, Rochester, New York, USA., Kadambi S; Division of Hematology/Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA., Klepin HD; Section on Hematology and Oncology, Department of Medicine, Wake Forest School of Medicine, Wake Forest, North Carolina, USA., Kyi K; Division of Hematology/Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA., Lowenstein LM; Department of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Phillips T; Department of Medical Oncology and Therapeutics, City of Hope, Antelope Valley, Duarte, California, USA., Ramsdale E; Division of Hematology/Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA., Schiaffino MK; Department of Radiation Medicine and Applied Sciences, University of California San Diego School of Medicine, La Jolla, California, USA., Simmons JF Jr; Cancer and Aging Research Group SCOREboard, City of Hope, Duarte, California, USA., Williams GR; Division of Hematology/Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA., Zittel J; Division of Hematology/Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA., Mohile S; Division of Hematology/Oncology, Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA.
Jazyk: angličtina
Zdroj: CA: a cancer journal for clinicians [CA Cancer J Clin] 2024 Nov-Dec; Vol. 74 (6), pp. 496-518. Date of Electronic Publication: 2024 Aug 29.
DOI: 10.3322/caac.21864
Abstrakt: Older adults with cancer heterogeneously experience health care, treatment, and symptoms. Geriatric assessment (GA) offers a comprehensive evaluation of an older individual's health status and can predict cancer-related outcomes in individuals with solid tumors and those with hematologic malignancies. In the last decade, randomized controlled trials have demonstrated the benefits of GA and GA management (GAM), which uses GA information to provide tailored intervention strategies to address GA impairments (e.g., implementing physical therapy for impaired physical function). Multiple phase 3 clinical trials in older adults with solid tumors and hematologic malignancies have demonstrated that GAM improves treatment completion, quality of life, communication, and advance care planning while reducing treatment-related toxicity, falls, and polypharmacy. Nonetheless, implementation and uptake of GAM remain challenging. Various strategies have been proposed, including the use of GA screening tools, to identify patients most likely to benefit from GAM, the systematic engagement of the oncology workforce in the delivery of GAM, and the integration of technologies like telemedicine and mobile health to enhance the availability of GA and GAM interventions. Health inequities in minoritized groups persist, and systematic GA implementation has the potential to capture social determinants of health that are relevant to equitable care. Caregivers play an important role in cancer care and experience burden themselves. GA can guide dyadic supportive care interventions, ultimately helping both patients and caregivers achieve optimal health.
(© 2024 The Author(s). CA: A Cancer Journal for Clinicians published by Wiley Periodicals LLC on behalf of American Cancer Society.)
Databáze: MEDLINE
Externí odkaz: