Diabetes Management Based on the Phenotype and Stage of the Disease: An Expert Proposal from the AGORA Diabetes Collaborative Group.

Autor: Gómez-Peralta F; Endocrinology and Nutrition Unit, Hospital General de Segovia, 40003 Segovia, Spain., Pinés-Corrales PJ; Endocrinology and Nutrition Service, Complejo Hospitalario Universitario de Albacete, 02008 Albacete, Spain., Santos E; Endocrinology and Nutrition Service, Complejo Hospitalario de Burgos, 09006 Burgos, Spain., Cuesta M; Endocrinology and Nutrition Service, Hospital Clínico San Carlos, 28040 Madrid, Spain., González-Albarrán O; Endocrinology and Nutrition Service, Hospital Gregorio Marañón, 28007 Madrid, Spain., Azriel S; Endocrinology and Nutrition Service, Hospital Universitario Infanta Sofía, 28702 San Sebastián De Los Reyes, Spain., On Behalf The Agora Diabetes Collaborative Group
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2024 Aug 16; Vol. 13 (16). Date of Electronic Publication: 2024 Aug 16.
DOI: 10.3390/jcm13164839
Abstrakt: Diabetes is a complex and rapidly growing disease with heterogeneous clinical presentations. Recent advances in molecular and genetic technologies have led to the identification of various subtypes of diabetes. These advancements offer the potential for a more precise, individualized approach to treatment, known as precision medicine. Recognizing high-risk phenotypes and intervening early and intensively is crucial. A staging system for type 1 diabetes has been proposed and accepted globally. In this article, we will explore the different methods for categorizing and classifying type 2 diabetes (T2D) based on clinical characteristics, progression patterns, risk of complications, and the use of molecular techniques for patient grouping. We, as a team of experts, will also present an easy-to-follow treatment plan and guidance for non-specialists, particularly primary care physicians, that integrates the classification and staging of diabetes. This will help ensure that the most suitable therapy is applied to the different types of T2D at each stage of the disease's progression.
Databáze: MEDLINE
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