| Autor: |
Zhang T; Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China., Yuan S; Department of Electronic Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China., Xu C; Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China., Liu P; Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China., Chang HC; Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China., Ng SHC; Department of Surgery, The Chinese University of Hong Kong, Hong Kong SAR, China., Ren H; Department of Electronic Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China., Yuan W; Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China. |
| Abstrakt: |
The complex anatomy of internal luminal organs, like bronchioles, poses challenges for endoscopic optical coherence tomography (OCT). These challenges include limited steerability for targeted imaging and nonuniform rotation distortion (NURD) with proximal scanning. Using rotary micromotors for distal scanning could address NURD but raises concerns about electrical safety and costs. We present pneumaOCT, the first pneumatic OCT endoscope, comprising a steerable catheter with a soft pneumatic actuator and an imaging probe with a miniature pneumatic turbine. With a diameter of 2.8 mm, pneumaOCT allows for a bending angle of up to 237°, facilitating navigation through narrow turns. The pneumatic turbine enables adjustable imaging speeds from 51 to 446 revolutions per second. We demonstrate the pneumaOCT in vivo imaging of mouse esophagus and colon, as well as targeted and distortion-free imaging of peripheral bronchioles in a bronchial phantom and a porcine lung. This advancement substantially improves endoscopic OCT for navigational imaging in curved and narrow lumens. |
